STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTRLChymotrypsin-like protease CTRL-1; Chymotrypsin like; Belongs to the peptidase S1 family (264 aa)    
Predicted Functional Partners:
CPA1
Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro; Belongs to the peptidase M14 family
   
 
 0.961
CPB1
M14 carboxypeptidases; Belongs to the peptidase M14 family
   
 
 0.960
CEL
Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family
   
 
 0.921
CELA3B
Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity
  
  
0.862
CELA2A
Chymotrypsin-like elastase family member 2A; Acts upon elastin
  
  
0.839
CELA2B
Chymotrypsin-like elastase family member 2B; Acts upon elastin; Belongs to the peptidase S1 family. Elastase subfamily
  
  
0.838
PSMB10
Proteasome subunit beta type-10; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides; Belongs to the peptidase T1B family
 
  
 
 0.803
CELA3A
Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity
  
  
0.757
CTRB1
Chymotrypsinogen B1; Belongs to the peptidase S1 family
  
  
0.731
CTRB2
Chymotrypsinogen B2; Belongs to the peptidase S1 family
  
  
0.730
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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