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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF75AZinc finger protein 75A; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (296 aa)    
Predicted Functional Partners:
TIGD7
Tigger transposable element derived 7; Belongs to the tigger transposable element derived protein family.
   
  
 0.621
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...]
   
 0.557
C14orf180
Nutritionally-regulated adipose and cardiac enriched protein homolog; Chromosome 14 open reading frame 180.
      
 0.556
ZNF395
Zinc finger protein 395; Plays a role in papillomavirus genes transcription.
   
 
 0.435
OR1F1
Olfactory receptor 1F1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.418
FLRT2
Leucine-rich repeat transmembrane protein FLRT2; Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells. May play a role in the migration of cortical neurons during brain development via its interaction with UNC5D. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5D, and possibly also other UNC-5 family members. Plays a role in fibroblast growth factor-mediated signal [...]
    
 
 0.404
FAM71B
Protein FAM71B; May be involved in RNA biogenesis.
      
 0.400
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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