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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBPF15Neuroblastoma breakpoint family member 15; NBPF member 15. (670 aa)    
Predicted Functional Partners:
NOTCH2NLB
Notch homolog 2 N-terminal-like protein B; Human-specific protein that promotes neural progenitor proliferation and evolutionary expansion of the brain neocortex by regulating the Notch signaling pathway. Able to promote neural progenitor self-renewal, possibly by down-regulating neuronal differentiation genes, thereby delaying the differentiation of neuronal progenitors and leading to an overall final increase in neuronal production. Acts by enhancing the Notch signaling pathway via two different mechanisms that probably work in parallel to reach the same effect. Enhances Notch signal [...]
      
 0.540
GOLGA8F
Golgin A8 family member F; Belongs to the GOLGA8 family.
   
 
 0.469
PPIAL4F
Peptidylprolyl isomerase A like 4F.
    
 
 0.464
PPIAL4D
Peptidyl-prolyl cis-trans isomerase A-like 4D; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity); Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.
    
 
 0.463
FAM72B
Protein FAM72B; Family with sequence similarity 72 member B; Belongs to the FAM72 family.
      
 0.461
USP17L11
Ubiquitin carboxyl-terminal hydrolase 17-like protein 11; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection.
    
 
 0.449
FAM47A
Protein FAM47A; Family with sequence similarity 47 member A.
  
 
   0.444
CPHXL
Cytoplasmic polyadenylated homeobox like.
  
 
 
 0.439
ENSP00000491197
Homeobox domain-containing protein.
  
 
 
 0.434
OR4F17
Olfactory receptor 4F17; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.421
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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