STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPIAL4HPeptidyl-prolyl cis-trans isomerase A-like 4H; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (164 aa)    
Predicted Functional Partners:
RANBP1
Ran-specific GTPase-activating protein; Plays a role in RAN-dependent nucleocytoplasmic transport. Alleviates the TNPO1-dependent inhibition of RAN GTPase activity and mediates the dissociation of RAN from proteins involved in transport into the nucleus (By similarity). Induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins. Promotes the disassembly of the complex formed by RAN and importin beta. Promotes dissociation of RAN from a complex with KPNA2 and CSE1L (By similarity). Required for normal mito [...]
 
 
 
 0.726
RGPD3
RANBP2 like and GRIP domain containing 3.
 
 
 
 0.580
RGPD5
RANBP2-like and GRIP domain-containing protein 5/6; RANBP2 like and GRIP domain containing 5.
 
 
 
 0.576
RGPD6
RANBP2 like and GRIP domain containing 6.
 
 
 
 0.576
RPS11
Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family.
   
 
 0.521
RGPD4
RANBP2 like and GRIP domain containing 4.
 
      0.521
RGPD2
RANBP2 like and GRIP domain containing 2.
 
      0.516
RGPD8
RANBP2 like and GRIP domain containing 8.
 
      0.515
RGPD1
RANBP2 like and GRIP domain containing 1.
 
      0.515
RPL3
60S ribosomal protein L3; The L3 protein is a component of the large subunit of cytoplasmic ribosomes.
   
 
 0.508
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.