STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF850Zinc finger protein 850; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (1090 aa)    
Predicted Functional Partners:
ZNF714
Zinc finger protein 714; May be involved in transcriptional regulation.
  
   
0.639
ZNF431
Zinc finger protein 431; Sequence-specific DNA binding transcriptional repressor. Represses target gene transcription by recruiting HDAC1 and HDAC2 histone deacetylases. Acts as a specific transcriptional repressor for PTCH1 during embryonic development. Required for osteoblast differentiation and sonic hedgehog/SHH signaling response. Binds to the consensus site 5'-GCGCCC-3' in the promoter of PTCH1 (By similarity). Belongs to the krueppel C2H2-type zinc-finger protein family.
  
   
0.545
SLC35E2A
Solute carrier family 35 member E2A; Putative transporter.
   
  
 0.516
MAGEB17
Melanoma-associated antigen B17; MAGE family member B17.
      
 0.507
CYP20A1
Cytochrome P450 family 20 subfamily A member 1.
   
 
 0.498
NOL9
Polynucleotide 5'-hydroxyl-kinase NOL9; Polynucleotide 5'-kinase involved in rRNA processing. The kinase activity is required for the processing of the 32S precursor into 5.8S and 28S rRNAs, more specifically for the generation of the major 5.8S(S) form. In vitro, has both DNA and RNA 5'-kinase activities. Probably binds RNA; Belongs to the Clp1 family. NOL9/GRC3 subfamily.
   
  
 0.496
SLC35E2B
Solute carrier family 35 member E2B; Putative transporter; Belongs to the TPT transporter family. SLC35E subfamily.
   
  
 0.489
PLCXD1
PI-PLC X domain-containing protein 1; Phosphatidylinositol specific phospholipase C X domain containing 1.
   
  
 0.478
OR2T4
Olfactory receptor 2T4; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.475
FAM47C
Putative protein FAM47C; Family with sequence similarity 47 member C; Belongs to the FAM47 family.
    
 
 0.452
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.