| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALPI | LY6G6D | ENSP00000295463 | ENSP00000364985 | Alkaline phosphatase, intestinal. | Lymphocyte antigen 6 family member G6D. | 0.400 |
| ALPI | LYPD8 | ENSP00000295463 | ENSP00000466070 | Alkaline phosphatase, intestinal. | Ly6/PLAUR domain-containing protein 8; Secreted protein specifically required to prevent invasion of Gram-negative bacteria in the inner mucus layer of the colon epithelium, a portion of the large intestine which is free of commensal microbiota. Prevents invasion of flagellated microbiota by binding to the flagellum of bacteria, such as P.mirabilis, thereby inhibiting bacterial motility in the intestinal lumen. Segregation of intestinal bacteria and epithelial cells in the colon is required to preserve intestinal homeostasis. | 0.442 |
| DIRC1 | LYPD8 | ENSP00000307860 | ENSP00000466070 | Disrupted in renal carcinoma 1. | Ly6/PLAUR domain-containing protein 8; Secreted protein specifically required to prevent invasion of Gram-negative bacteria in the inner mucus layer of the colon epithelium, a portion of the large intestine which is free of commensal microbiota. Prevents invasion of flagellated microbiota by binding to the flagellum of bacteria, such as P.mirabilis, thereby inhibiting bacterial motility in the intestinal lumen. Segregation of intestinal bacteria and epithelial cells in the colon is required to preserve intestinal homeostasis. | 0.436 |
| KRTAP19-6 | LYPD8 | ENSP00000375107 | ENSP00000466070 | Keratin-associated protein 19-6; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 19 family. | Ly6/PLAUR domain-containing protein 8; Secreted protein specifically required to prevent invasion of Gram-negative bacteria in the inner mucus layer of the colon epithelium, a portion of the large intestine which is free of commensal microbiota. Prevents invasion of flagellated microbiota by binding to the flagellum of bacteria, such as P.mirabilis, thereby inhibiting bacterial motility in the intestinal lumen. Segregation of intestinal bacteria and epithelial cells in the colon is required to preserve intestinal homeostasis. | 0.492 |
| LY6G6D | ALPI | ENSP00000364985 | ENSP00000295463 | Lymphocyte antigen 6 family member G6D. | Alkaline phosphatase, intestinal. | 0.400 |
| LY6G6D | LY6L | ENSP00000364985 | ENSP00000455811 | Lymphocyte antigen 6 family member G6D. | Lymphocyte antigen 6 family member L. | 0.446 |
| LY6G6D | LYPD8 | ENSP00000364985 | ENSP00000466070 | Lymphocyte antigen 6 family member G6D. | Ly6/PLAUR domain-containing protein 8; Secreted protein specifically required to prevent invasion of Gram-negative bacteria in the inner mucus layer of the colon epithelium, a portion of the large intestine which is free of commensal microbiota. Prevents invasion of flagellated microbiota by binding to the flagellum of bacteria, such as P.mirabilis, thereby inhibiting bacterial motility in the intestinal lumen. Segregation of intestinal bacteria and epithelial cells in the colon is required to preserve intestinal homeostasis. | 0.489 |
| LY6G6D | PATE3 | ENSP00000364985 | ENSP00000395505 | Lymphocyte antigen 6 family member G6D. | Prostate and testis expressed 3; Belongs to the PATE family. | 0.431 |
| LY6L | LY6G6D | ENSP00000455811 | ENSP00000364985 | Lymphocyte antigen 6 family member L. | Lymphocyte antigen 6 family member G6D. | 0.446 |
| LY6L | LYPD8 | ENSP00000455811 | ENSP00000466070 | Lymphocyte antigen 6 family member L. | Ly6/PLAUR domain-containing protein 8; Secreted protein specifically required to prevent invasion of Gram-negative bacteria in the inner mucus layer of the colon epithelium, a portion of the large intestine which is free of commensal microbiota. Prevents invasion of flagellated microbiota by binding to the flagellum of bacteria, such as P.mirabilis, thereby inhibiting bacterial motility in the intestinal lumen. Segregation of intestinal bacteria and epithelial cells in the colon is required to preserve intestinal homeostasis. | 0.480 |
| LY6L | PATE3 | ENSP00000455811 | ENSP00000395505 | Lymphocyte antigen 6 family member L. | Prostate and testis expressed 3; Belongs to the PATE family. | 0.761 |
| LY6L | PINLYP | ENSP00000455811 | ENSP00000479240 | Lymphocyte antigen 6 family member L. | Phospholipase A2 inhibitor and LY6/PLAUR domain containing; Belongs to the CNF-like-inhibitor family. | 0.717 |
| LYPD8 | ALPI | ENSP00000466070 | ENSP00000295463 | Ly6/PLAUR domain-containing protein 8; Secreted protein specifically required to prevent invasion of Gram-negative bacteria in the inner mucus layer of the colon epithelium, a portion of the large intestine which is free of commensal microbiota. Prevents invasion of flagellated microbiota by binding to the flagellum of bacteria, such as P.mirabilis, thereby inhibiting bacterial motility in the intestinal lumen. Segregation of intestinal bacteria and epithelial cells in the colon is required to preserve intestinal homeostasis. | Alkaline phosphatase, intestinal. | 0.442 |
| LYPD8 | DIRC1 | ENSP00000466070 | ENSP00000307860 | Ly6/PLAUR domain-containing protein 8; Secreted protein specifically required to prevent invasion of Gram-negative bacteria in the inner mucus layer of the colon epithelium, a portion of the large intestine which is free of commensal microbiota. Prevents invasion of flagellated microbiota by binding to the flagellum of bacteria, such as P.mirabilis, thereby inhibiting bacterial motility in the intestinal lumen. Segregation of intestinal bacteria and epithelial cells in the colon is required to preserve intestinal homeostasis. | Disrupted in renal carcinoma 1. | 0.436 |
| LYPD8 | KRTAP19-6 | ENSP00000466070 | ENSP00000375107 | Ly6/PLAUR domain-containing protein 8; Secreted protein specifically required to prevent invasion of Gram-negative bacteria in the inner mucus layer of the colon epithelium, a portion of the large intestine which is free of commensal microbiota. Prevents invasion of flagellated microbiota by binding to the flagellum of bacteria, such as P.mirabilis, thereby inhibiting bacterial motility in the intestinal lumen. Segregation of intestinal bacteria and epithelial cells in the colon is required to preserve intestinal homeostasis. | Keratin-associated protein 19-6; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 19 family. | 0.492 |
| LYPD8 | LY6G6D | ENSP00000466070 | ENSP00000364985 | Ly6/PLAUR domain-containing protein 8; Secreted protein specifically required to prevent invasion of Gram-negative bacteria in the inner mucus layer of the colon epithelium, a portion of the large intestine which is free of commensal microbiota. Prevents invasion of flagellated microbiota by binding to the flagellum of bacteria, such as P.mirabilis, thereby inhibiting bacterial motility in the intestinal lumen. Segregation of intestinal bacteria and epithelial cells in the colon is required to preserve intestinal homeostasis. | Lymphocyte antigen 6 family member G6D. | 0.489 |
| LYPD8 | LY6L | ENSP00000466070 | ENSP00000455811 | Ly6/PLAUR domain-containing protein 8; Secreted protein specifically required to prevent invasion of Gram-negative bacteria in the inner mucus layer of the colon epithelium, a portion of the large intestine which is free of commensal microbiota. Prevents invasion of flagellated microbiota by binding to the flagellum of bacteria, such as P.mirabilis, thereby inhibiting bacterial motility in the intestinal lumen. Segregation of intestinal bacteria and epithelial cells in the colon is required to preserve intestinal homeostasis. | Lymphocyte antigen 6 family member L. | 0.480 |
| LYPD8 | PATE3 | ENSP00000466070 | ENSP00000395505 | Ly6/PLAUR domain-containing protein 8; Secreted protein specifically required to prevent invasion of Gram-negative bacteria in the inner mucus layer of the colon epithelium, a portion of the large intestine which is free of commensal microbiota. Prevents invasion of flagellated microbiota by binding to the flagellum of bacteria, such as P.mirabilis, thereby inhibiting bacterial motility in the intestinal lumen. Segregation of intestinal bacteria and epithelial cells in the colon is required to preserve intestinal homeostasis. | Prostate and testis expressed 3; Belongs to the PATE family. | 0.420 |
| LYPD8 | PINLYP | ENSP00000466070 | ENSP00000479240 | Ly6/PLAUR domain-containing protein 8; Secreted protein specifically required to prevent invasion of Gram-negative bacteria in the inner mucus layer of the colon epithelium, a portion of the large intestine which is free of commensal microbiota. Prevents invasion of flagellated microbiota by binding to the flagellum of bacteria, such as P.mirabilis, thereby inhibiting bacterial motility in the intestinal lumen. Segregation of intestinal bacteria and epithelial cells in the colon is required to preserve intestinal homeostasis. | Phospholipase A2 inhibitor and LY6/PLAUR domain containing; Belongs to the CNF-like-inhibitor family. | 0.493 |
| LYPD8 | REG3A | ENSP00000466070 | ENSP00000377456 | Ly6/PLAUR domain-containing protein 8; Secreted protein specifically required to prevent invasion of Gram-negative bacteria in the inner mucus layer of the colon epithelium, a portion of the large intestine which is free of commensal microbiota. Prevents invasion of flagellated microbiota by binding to the flagellum of bacteria, such as P.mirabilis, thereby inhibiting bacterial motility in the intestinal lumen. Segregation of intestinal bacteria and epithelial cells in the colon is required to preserve intestinal homeostasis. | Regenerating islet-derived protein 3-alpha 16.5 kDa form; Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway. | 0.471 |
STRING v12.5 is now available!
