STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKRD62Ankyrin repeat domain 62. (917 aa)    
Predicted Functional Partners:
MTMR12
Myotubularin-related protein 12; Acts as an adapter for the myotubularin-related phosphatases. Regulates phosphatase MTM1 protein stability and possibly its intracellular location. By stabilizing MTM1 protein levels, required for skeletal muscle maintenance but not for myogenesis (By similarity). Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily.
    
 
 0.598
C3orf22
Uncharacterized protein C3orf22; Chromosome 3 open reading frame 22.
   
  
 0.589
C1orf167
Uncharacterized protein C1orf167; Chromosome 1 open reading frame 167.
   
  
 0.565
EEF2KMT
Protein-lysine N-methyltransferase EEF2KMT; Catalyzes the trimethylation of eukaryotic elongation factor 2 (EEF2) on 'Lys-525'.
      
 0.563
RNASE12
Probable inactive ribonuclease-like protein 12; Does not exhibit any ribonuclease activity; Belongs to the pancreatic ribonuclease family.
      
 0.544
C12orf56
Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.
      
 0.543
WDR97
WD repeat domain 97.
   
 
 0.534
SMIM17
Small integral membrane protein 17.
      
 0.527
CC2D2B
Protein CC2D2B; Coiled-coil and C2 domain containing 2B.
      
 0.509
SH2D7
SH2 domain containing 7.
      
 0.507
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.