| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMDHD1 | TMEM101 | ENSP00000266736 | ENSP00000468025 | Probable imidazolonepropionase; Amidohydrolase domain containing 1. | Transmembrane protein 101; May activate NF-kappa-B signaling pathways. | 0.494 |
| DSN1 | TMEM101 | ENSP00000389810 | ENSP00000468025 | Kinetochore-associated protein DSN1 homolog; Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. | Transmembrane protein 101; May activate NF-kappa-B signaling pathways. | 0.971 |
| HADHA | HADHB | ENSP00000370023 | ENSP00000325136 | Trifunctional enzyme subunit alpha, mitochondrial; Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long-chain fatty acids. Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional en [...] | Trifunctional enzyme subunit beta, mitochondrial; Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long- chain fatty acids. Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional en [...] | 0.999 |
| HADHA | TMEM101 | ENSP00000370023 | ENSP00000468025 | Trifunctional enzyme subunit alpha, mitochondrial; Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long-chain fatty acids. Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional en [...] | Transmembrane protein 101; May activate NF-kappa-B signaling pathways. | 0.524 |
| HADHB | HADHA | ENSP00000325136 | ENSP00000370023 | Trifunctional enzyme subunit beta, mitochondrial; Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long- chain fatty acids. Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional en [...] | Trifunctional enzyme subunit alpha, mitochondrial; Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long-chain fatty acids. Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional en [...] | 0.999 |
| HADHB | TMEM101 | ENSP00000325136 | ENSP00000468025 | Trifunctional enzyme subunit beta, mitochondrial; Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long- chain fatty acids. Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional en [...] | Transmembrane protein 101; May activate NF-kappa-B signaling pathways. | 0.555 |
| INIP | NOP14 | ENSP00000363360 | ENSP00000405068 | SOSS complex subunit C; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. | Nucleolar protein 14; Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity); Belongs to the NOP14 family. | 0.458 |
| INIP | TMEM101 | ENSP00000363360 | ENSP00000468025 | SOSS complex subunit C; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. | Transmembrane protein 101; May activate NF-kappa-B signaling pathways. | 0.511 |
| NOP14 | INIP | ENSP00000405068 | ENSP00000363360 | Nucleolar protein 14; Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity); Belongs to the NOP14 family. | SOSS complex subunit C; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. | 0.458 |
| NOP14 | TMEM101 | ENSP00000405068 | ENSP00000468025 | Nucleolar protein 14; Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity); Belongs to the NOP14 family. | Transmembrane protein 101; May activate NF-kappa-B signaling pathways. | 0.483 |
| TMEM101 | AMDHD1 | ENSP00000468025 | ENSP00000266736 | Transmembrane protein 101; May activate NF-kappa-B signaling pathways. | Probable imidazolonepropionase; Amidohydrolase domain containing 1. | 0.494 |
| TMEM101 | DSN1 | ENSP00000468025 | ENSP00000389810 | Transmembrane protein 101; May activate NF-kappa-B signaling pathways. | Kinetochore-associated protein DSN1 homolog; Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. | 0.971 |
| TMEM101 | HADHA | ENSP00000468025 | ENSP00000370023 | Transmembrane protein 101; May activate NF-kappa-B signaling pathways. | Trifunctional enzyme subunit alpha, mitochondrial; Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long-chain fatty acids. Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional en [...] | 0.524 |
| TMEM101 | HADHB | ENSP00000468025 | ENSP00000325136 | Transmembrane protein 101; May activate NF-kappa-B signaling pathways. | Trifunctional enzyme subunit beta, mitochondrial; Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long- chain fatty acids. Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional en [...] | 0.555 |
| TMEM101 | INIP | ENSP00000468025 | ENSP00000363360 | Transmembrane protein 101; May activate NF-kappa-B signaling pathways. | SOSS complex subunit C; Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. | 0.511 |
| TMEM101 | NOP14 | ENSP00000468025 | ENSP00000405068 | Transmembrane protein 101; May activate NF-kappa-B signaling pathways. | Nucleolar protein 14; Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity); Belongs to the NOP14 family. | 0.483 |
| TMEM101 | TMEM115 | ENSP00000468025 | ENSP00000266025 | Transmembrane protein 101; May activate NF-kappa-B signaling pathways. | Transmembrane protein 115; May play a role in retrograde transport of proteins from the Golgi to the endoplasmic reticulum. May indirectly play a role in protein glycosylation in the Golgi. | 0.498 |
| TMEM101 | TMEM208 | ENSP00000468025 | ENSP00000305892 | Transmembrane protein 101; May activate NF-kappa-B signaling pathways. | Transmembrane protein 208; May function as a negative regulator of endoplasmic reticulum-stress induced autophagy. | 0.528 |
| TMEM101 | TMEM223 | ENSP00000468025 | ENSP00000303987 | Transmembrane protein 101; May activate NF-kappa-B signaling pathways. | Transmembrane protein 223. | 0.547 |
| TMEM101 | TMEM59L | ENSP00000468025 | ENSP00000470879 | Transmembrane protein 101; May activate NF-kappa-B signaling pathways. | Transmembrane protein 59-like; Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding. | 0.500 |
