node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
K7EQZ3_HUMAN | PRSS1 | ENSP00000468040 | ENSP00000308720 | BPTI/Kunitz inhibitor domain-containing protein. | Alpha-trypsin chain 1; Has activity against the synthetic substrates Boc-Phe-Ser- Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg- Mec. The single-chain form is more active than the two-chain form against all of these substrates; Belongs to the peptidase S1 family. | 0.495 |
K7EQZ3_HUMAN | PRSS2 | ENSP00000468040 | ENSP00000488437 | BPTI/Kunitz inhibitor domain-containing protein. | Trypsin-2; In the ileum, may be involved in defensin processing, including DEFA5; Belongs to the peptidase S1 family. | 0.495 |
K7EQZ3_HUMAN | PRSS3 | ENSP00000468040 | ENSP00000354280 | BPTI/Kunitz inhibitor domain-containing protein. | Trypsin-3; Digestive protease that cleaves proteins preferentially after an Arg residue and has proteolytic activity toward Kunitz-type trypsin inhibitors. Belongs to the peptidase S1 family. | 0.448 |
K7EQZ3_HUMAN | SPINT3 | ENSP00000468040 | ENSP00000217428 | BPTI/Kunitz inhibitor domain-containing protein. | Serine peptidase inhibitor, Kunitz type 3. | 0.518 |
PRSS1 | K7EQZ3_HUMAN | ENSP00000308720 | ENSP00000468040 | Alpha-trypsin chain 1; Has activity against the synthetic substrates Boc-Phe-Ser- Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg- Mec. The single-chain form is more active than the two-chain form against all of these substrates; Belongs to the peptidase S1 family. | BPTI/Kunitz inhibitor domain-containing protein. | 0.495 |
PRSS1 | PRSS2 | ENSP00000308720 | ENSP00000488437 | Alpha-trypsin chain 1; Has activity against the synthetic substrates Boc-Phe-Ser- Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg- Mec. The single-chain form is more active than the two-chain form against all of these substrates; Belongs to the peptidase S1 family. | Trypsin-2; In the ileum, may be involved in defensin processing, including DEFA5; Belongs to the peptidase S1 family. | 0.705 |
PRSS1 | PRSS3 | ENSP00000308720 | ENSP00000354280 | Alpha-trypsin chain 1; Has activity against the synthetic substrates Boc-Phe-Ser- Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg- Mec. The single-chain form is more active than the two-chain form against all of these substrates; Belongs to the peptidase S1 family. | Trypsin-3; Digestive protease that cleaves proteins preferentially after an Arg residue and has proteolytic activity toward Kunitz-type trypsin inhibitors. Belongs to the peptidase S1 family. | 0.918 |
PRSS2 | K7EQZ3_HUMAN | ENSP00000488437 | ENSP00000468040 | Trypsin-2; In the ileum, may be involved in defensin processing, including DEFA5; Belongs to the peptidase S1 family. | BPTI/Kunitz inhibitor domain-containing protein. | 0.495 |
PRSS2 | PRSS1 | ENSP00000488437 | ENSP00000308720 | Trypsin-2; In the ileum, may be involved in defensin processing, including DEFA5; Belongs to the peptidase S1 family. | Alpha-trypsin chain 1; Has activity against the synthetic substrates Boc-Phe-Ser- Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg- Mec. The single-chain form is more active than the two-chain form against all of these substrates; Belongs to the peptidase S1 family. | 0.705 |
PRSS2 | PRSS3 | ENSP00000488437 | ENSP00000354280 | Trypsin-2; In the ileum, may be involved in defensin processing, including DEFA5; Belongs to the peptidase S1 family. | Trypsin-3; Digestive protease that cleaves proteins preferentially after an Arg residue and has proteolytic activity toward Kunitz-type trypsin inhibitors. Belongs to the peptidase S1 family. | 0.999 |
PRSS3 | K7EQZ3_HUMAN | ENSP00000354280 | ENSP00000468040 | Trypsin-3; Digestive protease that cleaves proteins preferentially after an Arg residue and has proteolytic activity toward Kunitz-type trypsin inhibitors. Belongs to the peptidase S1 family. | BPTI/Kunitz inhibitor domain-containing protein. | 0.448 |
PRSS3 | PRSS1 | ENSP00000354280 | ENSP00000308720 | Trypsin-3; Digestive protease that cleaves proteins preferentially after an Arg residue and has proteolytic activity toward Kunitz-type trypsin inhibitors. Belongs to the peptidase S1 family. | Alpha-trypsin chain 1; Has activity against the synthetic substrates Boc-Phe-Ser- Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg- Mec. The single-chain form is more active than the two-chain form against all of these substrates; Belongs to the peptidase S1 family. | 0.918 |
PRSS3 | PRSS2 | ENSP00000354280 | ENSP00000488437 | Trypsin-3; Digestive protease that cleaves proteins preferentially after an Arg residue and has proteolytic activity toward Kunitz-type trypsin inhibitors. Belongs to the peptidase S1 family. | Trypsin-2; In the ileum, may be involved in defensin processing, including DEFA5; Belongs to the peptidase S1 family. | 0.999 |
SPINT3 | K7EQZ3_HUMAN | ENSP00000217428 | ENSP00000468040 | Serine peptidase inhibitor, Kunitz type 3. | BPTI/Kunitz inhibitor domain-containing protein. | 0.518 |