node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CTAG2 | MAGEA4 | ENSP00000247306 | ENSP00000353379 | Cancer/testis antigen 2; Belongs to the CTAG/PCC1 family. | Melanoma-associated antigen 4; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. | 0.924 |
CTAG2 | MAGEC1 | ENSP00000247306 | ENSP00000285879 | Cancer/testis antigen 2; Belongs to the CTAG/PCC1 family. | Melanoma-associated antigen C1; MAGE family member C1. | 0.723 |
CTAG2 | SSX4 | ENSP00000247306 | ENSP00000469011 | Cancer/testis antigen 2; Belongs to the CTAG/PCC1 family. | Protein SSX4; Could act as a modulator of transcription. | 0.646 |
CTAG2 | SSX4B | ENSP00000247306 | ENSP00000469394 | Cancer/testis antigen 2; Belongs to the CTAG/PCC1 family. | SSX family member 4B. | 0.625 |
MAGEA4 | CTAG2 | ENSP00000353379 | ENSP00000247306 | Melanoma-associated antigen 4; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. | Cancer/testis antigen 2; Belongs to the CTAG/PCC1 family. | 0.924 |
MAGEA4 | SSX4 | ENSP00000353379 | ENSP00000469011 | Melanoma-associated antigen 4; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. | Protein SSX4; Could act as a modulator of transcription. | 0.642 |
MAGEA4 | SSX4B | ENSP00000353379 | ENSP00000469394 | Melanoma-associated antigen 4; Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. | SSX family member 4B. | 0.626 |
MAGEC1 | CTAG2 | ENSP00000285879 | ENSP00000247306 | Melanoma-associated antigen C1; MAGE family member C1. | Cancer/testis antigen 2; Belongs to the CTAG/PCC1 family. | 0.723 |
MAGEC1 | SSX4 | ENSP00000285879 | ENSP00000469011 | Melanoma-associated antigen C1; MAGE family member C1. | Protein SSX4; Could act as a modulator of transcription. | 0.669 |
MAGEC1 | SSX4B | ENSP00000285879 | ENSP00000469394 | Melanoma-associated antigen C1; MAGE family member C1. | SSX family member 4B. | 0.656 |
SS18 | SSX4 | ENSP00000414516 | ENSP00000469011 | Protein SSXT; Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. | Protein SSX4; Could act as a modulator of transcription. | 0.930 |
SS18 | SSX4B | ENSP00000414516 | ENSP00000469394 | Protein SSXT; Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. | SSX family member 4B. | 0.932 |
SS18 | ZNF117 | ENSP00000414516 | ENSP00000282869 | Protein SSXT; Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. | Zinc finger protein 117; May be involved in transcriptional regulation. | 0.770 |
SS18 | ZNF83 | ENSP00000414516 | ENSP00000472619 | Protein SSXT; Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. | Zinc finger protein 83; May be involved in transcriptional regulation. | 0.772 |
SS18L1 | SSX4 | ENSP00000333012 | ENSP00000469011 | Calcium-responsive transactivator; Transcriptional activator which is required for calcium- dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is depho [...] | Protein SSX4; Could act as a modulator of transcription. | 0.817 |
SS18L1 | SSX4B | ENSP00000333012 | ENSP00000469394 | Calcium-responsive transactivator; Transcriptional activator which is required for calcium- dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is depho [...] | SSX family member 4B. | 0.833 |
SS18L2 | SSX4 | ENSP00000401115 | ENSP00000469011 | SS18-like protein 2; SS18 like 2. | Protein SSX4; Could act as a modulator of transcription. | 0.720 |
SS18L2 | SSX4B | ENSP00000401115 | ENSP00000469394 | SS18-like protein 2; SS18 like 2. | SSX family member 4B. | 0.750 |
SSX2IP | SSX4 | ENSP00000340279 | ENSP00000469011 | Afadin- and alpha-actinin-binding protein; Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin- catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha- actinin (By similarity). Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via [...] | Protein SSX4; Could act as a modulator of transcription. | 0.806 |
SSX2IP | SSX4B | ENSP00000340279 | ENSP00000469394 | Afadin- and alpha-actinin-binding protein; Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin- catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha- actinin (By similarity). Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via [...] | SSX family member 4B. | 0.808 |