RNF225 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALG10B	RNF225	ENSP00000310120	ENSP00000470441	Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase; Putative alpha-1,2-glucosyltransferase, which adds the third glucose residue to the lipid-linked oligosaccharide precursor for N- linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol (By similarity). When coupled to KCNH2 may reduce KCNH2 sensitivity to classic proarrhythmic drug blockade, possibly by mediating glycosylation of KCNH2. Has a role in maintenance of cochlear outer hair cell function (By similarity).	Ring finger protein 225.	0.473
CGB1	ENSP00000466140	ENSP00000301407	ENSP00000466140	Chorionic gonadotropin subunit beta 1.	Novel protein.	0.884
CGB1	RNF225	ENSP00000301407	ENSP00000470441	Chorionic gonadotropin subunit beta 1.	Ring finger protein 225.	0.435
ENSP00000466140	CGB1	ENSP00000466140	ENSP00000301407	Novel protein.	Chorionic gonadotropin subunit beta 1.	0.884
ENSP00000466140	RNF225	ENSP00000466140	ENSP00000470441	Novel protein.	Ring finger protein 225.	0.439
GASK1A	RNF225	ENSP00000407301	ENSP00000470441	Golgi associated kinase 1A; Belongs to the GASK family.	Ring finger protein 225.	0.571
OR4D6	RNF225	ENSP00000300127	ENSP00000470441	Olfactory receptor 4D6; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.	Ring finger protein 225.	0.547
PIR	RNF225	ENSP00000369786	ENSP00000470441	Pirin; Transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox- state-dependent manner. May be required for efficient terminal myeloid maturation of hematopoietic cells. Has quercetin 2,3-dioxygenase activity (in vitro). Belongs to the pirin family.	Ring finger protein 225.	0.433
RNF225	ALG10B	ENSP00000470441	ENSP00000310120	Ring finger protein 225.	Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase; Putative alpha-1,2-glucosyltransferase, which adds the third glucose residue to the lipid-linked oligosaccharide precursor for N- linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol (By similarity). When coupled to KCNH2 may reduce KCNH2 sensitivity to classic proarrhythmic drug blockade, possibly by mediating glycosylation of KCNH2. Has a role in maintenance of cochlear outer hair cell function (By similarity).	0.473
RNF225	CGB1	ENSP00000470441	ENSP00000301407	Ring finger protein 225.	Chorionic gonadotropin subunit beta 1.	0.435
RNF225	ENSP00000466140	ENSP00000470441	ENSP00000466140	Ring finger protein 225.	Novel protein.	0.439
RNF225	GASK1A	ENSP00000470441	ENSP00000407301	Ring finger protein 225.	Golgi associated kinase 1A; Belongs to the GASK family.	0.571
RNF225	OR4D6	ENSP00000470441	ENSP00000300127	Ring finger protein 225.	Olfactory receptor 4D6; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.	0.547
RNF225	PIR	ENSP00000470441	ENSP00000369786	Ring finger protein 225.	Pirin; Transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox- state-dependent manner. May be required for efficient terminal myeloid maturation of hematopoietic cells. Has quercetin 2,3-dioxygenase activity (in vitro). Belongs to the pirin family.	0.433
RNF225	SPANXD	ENSP00000470441	ENSP00000359546	Ring finger protein 225.	Sperm protein associated with the nucleus on the X chromosome D; SPANX family member D; Belongs to the SPAN-X family.	0.437
RNF225	ZNF584	ENSP00000470441	ENSP00000306756	Ring finger protein 225.	Zinc finger protein 584; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.	0.470
SPANXD	RNF225	ENSP00000359546	ENSP00000470441	Sperm protein associated with the nucleus on the X chromosome D; SPANX family member D; Belongs to the SPAN-X family.	Ring finger protein 225.	0.437
ZNF584	RNF225	ENSP00000306756	ENSP00000470441	Zinc finger protein 584; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.	Ring finger protein 225.	0.470