DMRTC1 protein (human) - STRING interaction network

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Predicted Interactions

gene neighborhood

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textmining

co-expression

protein homology

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[Homology]

Score

DMRTC1

DMRT like family C1. (192 aa)

Predicted Functional Partners:

DMRTC1B

0.786

CHIC1

0.540

CTPS2

0.473

CDX4

0.418

HS6ST2

0.418

RLIM

0.403

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDX4	CHIC1	ENSP00000362613	ENSP00000362601	Homeobox protein CDX-4; Caudal type homeobox 4; Belongs to the Caudal homeobox family.	Cysteine-rich hydrophobic domain-containing protein 1; Cysteine rich hydrophobic domain 1; Belongs to the CHIC family.	0.595
CDX4	DMRTC1	ENSP00000362613	ENSP00000471224	Homeobox protein CDX-4; Caudal type homeobox 4; Belongs to the Caudal homeobox family.	DMRT like family C1.	0.418
CDX4	RLIM	ENSP00000362613	ENSP00000328059	Homeobox protein CDX-4; Caudal type homeobox 4; Belongs to the Caudal homeobox family.	E3 ubiquitin-protein ligase RLIM; E3 ubiquitin-protein ligase. Acts as a negative coregulator for LIM homeodomain transcription factors by mediating the ubiquitination and subsequent degradation of LIM cofactors LDB1 and LDB2 and by mediating the recruitment the SIN3a/histone deacetylase corepressor complex. Ubiquitination and degradation of LIM cofactors LDB1 and LDB2 allows DNA-bound LIM homeodomain transcription factors to interact with other protein partners such as RLIM. Plays a role in telomere length-mediated growth suppression by mediating the ubiquitination and degradation of [...]	0.411
CHIC1	CDX4	ENSP00000362601	ENSP00000362613	Cysteine-rich hydrophobic domain-containing protein 1; Cysteine rich hydrophobic domain 1; Belongs to the CHIC family.	Homeobox protein CDX-4; Caudal type homeobox 4; Belongs to the Caudal homeobox family.	0.595
CHIC1	DMRTC1	ENSP00000362601	ENSP00000471224	Cysteine-rich hydrophobic domain-containing protein 1; Cysteine rich hydrophobic domain 1; Belongs to the CHIC family.	DMRT like family C1.	0.540
CHIC1	DMRTC1B	ENSP00000362601	ENSP00000334501	Cysteine-rich hydrophobic domain-containing protein 1; Cysteine rich hydrophobic domain 1; Belongs to the CHIC family.	Doublesex- and mab-3-related transcription factor C1; DMRT like family C1B; Belongs to the DMRT family.	0.407
CHIC1	RLIM	ENSP00000362601	ENSP00000328059	Cysteine-rich hydrophobic domain-containing protein 1; Cysteine rich hydrophobic domain 1; Belongs to the CHIC family.	E3 ubiquitin-protein ligase RLIM; E3 ubiquitin-protein ligase. Acts as a negative coregulator for LIM homeodomain transcription factors by mediating the ubiquitination and subsequent degradation of LIM cofactors LDB1 and LDB2 and by mediating the recruitment the SIN3a/histone deacetylase corepressor complex. Ubiquitination and degradation of LIM cofactors LDB1 and LDB2 allows DNA-bound LIM homeodomain transcription factors to interact with other protein partners such as RLIM. Plays a role in telomere length-mediated growth suppression by mediating the ubiquitination and degradation of [...]	0.718
CTPS2	DMRTC1	ENSP00000401264	ENSP00000471224	CTP synthase 2; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides.	DMRT like family C1.	0.473
DMRTC1	CDX4	ENSP00000471224	ENSP00000362613	DMRT like family C1.	Homeobox protein CDX-4; Caudal type homeobox 4; Belongs to the Caudal homeobox family.	0.418
DMRTC1	CHIC1	ENSP00000471224	ENSP00000362601	DMRT like family C1.	Cysteine-rich hydrophobic domain-containing protein 1; Cysteine rich hydrophobic domain 1; Belongs to the CHIC family.	0.540
DMRTC1	CTPS2	ENSP00000471224	ENSP00000401264	DMRT like family C1.	CTP synthase 2; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides.	0.473
DMRTC1	DMRTC1B	ENSP00000471224	ENSP00000334501	DMRT like family C1.	Doublesex- and mab-3-related transcription factor C1; DMRT like family C1B; Belongs to the DMRT family.	0.786
DMRTC1	HS6ST2	ENSP00000471224	ENSP00000429473	DMRT like family C1.	Heparan-sulfate 6-O-sulfotransferase 2; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.	0.418
DMRTC1	RLIM	ENSP00000471224	ENSP00000328059	DMRT like family C1.	E3 ubiquitin-protein ligase RLIM; E3 ubiquitin-protein ligase. Acts as a negative coregulator for LIM homeodomain transcription factors by mediating the ubiquitination and subsequent degradation of LIM cofactors LDB1 and LDB2 and by mediating the recruitment the SIN3a/histone deacetylase corepressor complex. Ubiquitination and degradation of LIM cofactors LDB1 and LDB2 allows DNA-bound LIM homeodomain transcription factors to interact with other protein partners such as RLIM. Plays a role in telomere length-mediated growth suppression by mediating the ubiquitination and degradation of [...]	0.403
DMRTC1B	CHIC1	ENSP00000334501	ENSP00000362601	Doublesex- and mab-3-related transcription factor C1; DMRT like family C1B; Belongs to the DMRT family.	Cysteine-rich hydrophobic domain-containing protein 1; Cysteine rich hydrophobic domain 1; Belongs to the CHIC family.	0.407
DMRTC1B	DMRTC1	ENSP00000334501	ENSP00000471224	Doublesex- and mab-3-related transcription factor C1; DMRT like family C1B; Belongs to the DMRT family.	DMRT like family C1.	0.786
HS6ST2	DMRTC1	ENSP00000429473	ENSP00000471224	Heparan-sulfate 6-O-sulfotransferase 2; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.	DMRT like family C1.	0.418
RLIM	CDX4	ENSP00000328059	ENSP00000362613	E3 ubiquitin-protein ligase RLIM; E3 ubiquitin-protein ligase. Acts as a negative coregulator for LIM homeodomain transcription factors by mediating the ubiquitination and subsequent degradation of LIM cofactors LDB1 and LDB2 and by mediating the recruitment the SIN3a/histone deacetylase corepressor complex. Ubiquitination and degradation of LIM cofactors LDB1 and LDB2 allows DNA-bound LIM homeodomain transcription factors to interact with other protein partners such as RLIM. Plays a role in telomere length-mediated growth suppression by mediating the ubiquitination and degradation of [...]	Homeobox protein CDX-4; Caudal type homeobox 4; Belongs to the Caudal homeobox family.	0.411
RLIM	CHIC1	ENSP00000328059	ENSP00000362601	E3 ubiquitin-protein ligase RLIM; E3 ubiquitin-protein ligase. Acts as a negative coregulator for LIM homeodomain transcription factors by mediating the ubiquitination and subsequent degradation of LIM cofactors LDB1 and LDB2 and by mediating the recruitment the SIN3a/histone deacetylase corepressor complex. Ubiquitination and degradation of LIM cofactors LDB1 and LDB2 allows DNA-bound LIM homeodomain transcription factors to interact with other protein partners such as RLIM. Plays a role in telomere length-mediated growth suppression by mediating the ubiquitination and degradation of [...]	Cysteine-rich hydrophobic domain-containing protein 1; Cysteine rich hydrophobic domain 1; Belongs to the CHIC family.	0.718
RLIM	DMRTC1	ENSP00000328059	ENSP00000471224	E3 ubiquitin-protein ligase RLIM; E3 ubiquitin-protein ligase. Acts as a negative coregulator for LIM homeodomain transcription factors by mediating the ubiquitination and subsequent degradation of LIM cofactors LDB1 and LDB2 and by mediating the recruitment the SIN3a/histone deacetylase corepressor complex. Ubiquitination and degradation of LIM cofactors LDB1 and LDB2 allows DNA-bound LIM homeodomain transcription factors to interact with other protein partners such as RLIM. Plays a role in telomere length-mediated growth suppression by mediating the ubiquitination and degradation of [...]	DMRT like family C1.	0.403