ANKDD1B protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKDD1B	ANKRA2	ENSP00000471417	ENSP00000296785	Ankyrin repeat and death domain containing 1B.	Ankyrin repeat family A protein 2; May regulate the interaction between the 3M complex and the histone deacetylases HDAC4 and HDAC5. May also regulate LRP2/megalin (By similarity).	0.410
ANKDD1B	ASZ1	ENSP00000471417	ENSP00000284629	Ankyrin repeat and death domain containing 1B.	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1; Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the p [...]	0.412
ANKDD1B	CDH24	ENSP00000471417	ENSP00000380517	Ankyrin repeat and death domain containing 1B.	Cadherin-24; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Cadherin-24 mediate strong cell-cell adhesion.	0.500
ANKDD1B	KCNK5	ENSP00000471417	ENSP00000352527	Ankyrin repeat and death domain containing 1B.	Potassium channel subfamily K member 5; pH-dependent, voltage insensitive, outwardly rectifying potassium channel. Outward rectification is lost at high external K(+) concentrations.	0.442
ANKDD1B	KIF14	ENSP00000471417	ENSP00000356319	Ankyrin repeat and death domain containing 1B.	Kinesin-like protein KIF14; Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis. During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively. Regulates cell growth through regulation of cell cycle progression and cytokinesis. During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic [...]	0.470
ANKDD1B	MOB3C	ENSP00000471417	ENSP00000271139	Ankyrin repeat and death domain containing 1B.	MOB kinase activator 3C; May regulate the activity of kinases; Belongs to the MOB1/phocein family.	0.511
ANKDD1B	OR4X1	ENSP00000471417	ENSP00000321506	Ankyrin repeat and death domain containing 1B.	Olfactory receptor 4X1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.	0.497
ANKDD1B	OR51Q1	ENSP00000471417	ENSP00000300778	Ankyrin repeat and death domain containing 1B.	Olfactory receptor 51Q1; Odorant receptor.	0.413
ANKDD1B	TMC3	ENSP00000471417	ENSP00000352413	Ankyrin repeat and death domain containing 1B.	Transmembrane channel-like protein 3; Probable ion channel.	0.425
ANKDD1B	ZNF787	ENSP00000471417	ENSP00000478557	Ankyrin repeat and death domain containing 1B.	Zinc finger protein 787; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.	0.510
ANKRA2	ANKDD1B	ENSP00000296785	ENSP00000471417	Ankyrin repeat family A protein 2; May regulate the interaction between the 3M complex and the histone deacetylases HDAC4 and HDAC5. May also regulate LRP2/megalin (By similarity).	Ankyrin repeat and death domain containing 1B.	0.410
ASZ1	ANKDD1B	ENSP00000284629	ENSP00000471417	Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1; Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the p [...]	Ankyrin repeat and death domain containing 1B.	0.412
CDH24	ANKDD1B	ENSP00000380517	ENSP00000471417	Cadherin-24; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Cadherin-24 mediate strong cell-cell adhesion.	Ankyrin repeat and death domain containing 1B.	0.500
CDH24	ZNF787	ENSP00000380517	ENSP00000478557	Cadherin-24; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Cadherin-24 mediate strong cell-cell adhesion.	Zinc finger protein 787; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.	0.481
KCNK5	ANKDD1B	ENSP00000352527	ENSP00000471417	Potassium channel subfamily K member 5; pH-dependent, voltage insensitive, outwardly rectifying potassium channel. Outward rectification is lost at high external K(+) concentrations.	Ankyrin repeat and death domain containing 1B.	0.442
KIF14	ANKDD1B	ENSP00000356319	ENSP00000471417	Kinesin-like protein KIF14; Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis. During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively. Regulates cell growth through regulation of cell cycle progression and cytokinesis. During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic [...]	Ankyrin repeat and death domain containing 1B.	0.470
MOB3C	ANKDD1B	ENSP00000271139	ENSP00000471417	MOB kinase activator 3C; May regulate the activity of kinases; Belongs to the MOB1/phocein family.	Ankyrin repeat and death domain containing 1B.	0.511
OR4X1	ANKDD1B	ENSP00000321506	ENSP00000471417	Olfactory receptor 4X1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.	Ankyrin repeat and death domain containing 1B.	0.497
OR4X1	TMC3	ENSP00000321506	ENSP00000352413	Olfactory receptor 4X1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.	Transmembrane channel-like protein 3; Probable ion channel.	0.441
OR51Q1	ANKDD1B	ENSP00000300778	ENSP00000471417	Olfactory receptor 51Q1; Odorant receptor.	Ankyrin repeat and death domain containing 1B.	0.413