node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CACNA1B | SCGB1C2 | ENSP00000360423 | ENSP00000471646 | Voltage-dependent N-type calcium channel subunit alpha-1B; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group and are specifically blocked by omega-conotoxin- GVIA (AC P01522) (AC P01522) (By similarity). They are h [...] | Secretoglobin family 1C member 2. | 0.415 |
MST1 | SCGB1C2 | ENSP00000414287 | ENSP00000471646 | Hepatocyte growth factor-like protein alpha chain; Macrophage stimulating 1. | Secretoglobin family 1C member 2. | 0.415 |
PTPN20 | SCGB1C2 | ENSP00000363459 | ENSP00000471646 | Tyrosine-protein phosphatase non-receptor type 20; Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli. Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. | Secretoglobin family 1C member 2. | 0.409 |
PTPN20 | TCAF1 | ENSP00000363459 | ENSP00000419235 | Tyrosine-protein phosphatase non-receptor type 20; Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli. Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. | TRPM8 channel-associated factor 1; Positively regulates the plasma membrane cation channel TRPM8 activity. Involved in the recruitment of TRPM8 to the cell surface. Promotes prostate cancer cell migration inhibition in a TRPM8-dependent manner. | 0.532 |
SCGB1C2 | CACNA1B | ENSP00000471646 | ENSP00000360423 | Secretoglobin family 1C member 2. | Voltage-dependent N-type calcium channel subunit alpha-1B; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group and are specifically blocked by omega-conotoxin- GVIA (AC P01522) (AC P01522) (By similarity). They are h [...] | 0.415 |
SCGB1C2 | MST1 | ENSP00000471646 | ENSP00000414287 | Secretoglobin family 1C member 2. | Hepatocyte growth factor-like protein alpha chain; Macrophage stimulating 1. | 0.415 |
SCGB1C2 | PTPN20 | ENSP00000471646 | ENSP00000363459 | Secretoglobin family 1C member 2. | Tyrosine-protein phosphatase non-receptor type 20; Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli. Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. | 0.409 |
SCGB1C2 | SCGB3A2 | ENSP00000471646 | ENSP00000296694 | Secretoglobin family 1C member 2. | Secretoglobin family 3A member 2; Secreted cytokine-like protein. Binds to the scavenger receptor MARCO. Can also bind to pathogens including the Gram-positive bacterium L.monocytogenes, the Gram-negative bacterium P.aeruginosa, and yeast. Strongly inhibits phospholipase A2 (PLA2G1B) activity. Seems to have anti-inflammatory effects in respiratory epithelium (By similarity). Also has anti-fibrotic activity in lung. May play a role in fetal lung development and maturation. Promotes branching morphogenesis during early stages of lung development. In the pituitary, may inhibit production [...] | 0.463 |
SCGB1C2 | TBC1D3D | ENSP00000471646 | ENSP00000478426 | Secretoglobin family 1C member 2. | TBC1 domain family member 3D; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity). | 0.418 |
SCGB1C2 | TBC1D3H | ENSP00000471646 | ENSP00000482630 | Secretoglobin family 1C member 2. | TBC1 domain family member 3H; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity). | 0.471 |
SCGB1C2 | TBC1D3K | ENSP00000471646 | ENSP00000484181 | Secretoglobin family 1C member 2. | TBC1 domain family member 3K; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity). | 0.542 |
SCGB1C2 | TCAF1 | ENSP00000471646 | ENSP00000419235 | Secretoglobin family 1C member 2. | TRPM8 channel-associated factor 1; Positively regulates the plasma membrane cation channel TRPM8 activity. Involved in the recruitment of TRPM8 to the cell surface. Promotes prostate cancer cell migration inhibition in a TRPM8-dependent manner. | 0.412 |
SCGB3A2 | SCGB1C2 | ENSP00000296694 | ENSP00000471646 | Secretoglobin family 3A member 2; Secreted cytokine-like protein. Binds to the scavenger receptor MARCO. Can also bind to pathogens including the Gram-positive bacterium L.monocytogenes, the Gram-negative bacterium P.aeruginosa, and yeast. Strongly inhibits phospholipase A2 (PLA2G1B) activity. Seems to have anti-inflammatory effects in respiratory epithelium (By similarity). Also has anti-fibrotic activity in lung. May play a role in fetal lung development and maturation. Promotes branching morphogenesis during early stages of lung development. In the pituitary, may inhibit production [...] | Secretoglobin family 1C member 2. | 0.463 |
TBC1D3D | SCGB1C2 | ENSP00000478426 | ENSP00000471646 | TBC1 domain family member 3D; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity). | Secretoglobin family 1C member 2. | 0.418 |
TBC1D3H | SCGB1C2 | ENSP00000482630 | ENSP00000471646 | TBC1 domain family member 3H; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity). | Secretoglobin family 1C member 2. | 0.471 |
TBC1D3K | SCGB1C2 | ENSP00000484181 | ENSP00000471646 | TBC1 domain family member 3K; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity). | Secretoglobin family 1C member 2. | 0.542 |
TCAF1 | PTPN20 | ENSP00000419235 | ENSP00000363459 | TRPM8 channel-associated factor 1; Positively regulates the plasma membrane cation channel TRPM8 activity. Involved in the recruitment of TRPM8 to the cell surface. Promotes prostate cancer cell migration inhibition in a TRPM8-dependent manner. | Tyrosine-protein phosphatase non-receptor type 20; Tyrosine-protein phosphatase targeted to sites of actin polymerization in response of varied extracellular stimuli. Has tyrosine phosphatase activity towards various tyrosyl phosphorylated substrates; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. | 0.532 |
TCAF1 | SCGB1C2 | ENSP00000419235 | ENSP00000471646 | TRPM8 channel-associated factor 1; Positively regulates the plasma membrane cation channel TRPM8 activity. Involved in the recruitment of TRPM8 to the cell surface. Promotes prostate cancer cell migration inhibition in a TRPM8-dependent manner. | Secretoglobin family 1C member 2. | 0.412 |