| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFF2 | FMR1 | ENSP00000359489 | ENSP00000359506 | AF4/FMR2 family member 2; RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure. | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export (By similarity). Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons (By similarity). Stabilizes the scaffolding postsyna [...] | 0.940 |
| AFF2 | FRA10AC1 | ENSP00000359489 | ENSP00000360488 | AF4/FMR2 family member 2; RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure. | Protein FRA10AC1; FRA10A associated CGG repeat 1. | 0.500 |
| AFF2 | TMEM185A | ENSP00000359489 | ENSP00000471932 | AF4/FMR2 family member 2; RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure. | Transmembrane protein 185A; Belongs to the TMEM185 family. | 0.948 |
| ATP6V0D1 | ATP6V0D2 | ENSP00000290949 | ENSP00000285393 | V-type proton ATPase subunit d 1; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity). May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity). In aerobic conditions, involved in intracellular iron homeostasis, thus tri [...] | V-type proton ATPase subunit d 2; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity). | 0.999 |
| ATP6V0D1 | TMEM185A | ENSP00000290949 | ENSP00000471932 | V-type proton ATPase subunit d 1; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity). May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity). In aerobic conditions, involved in intracellular iron homeostasis, thus tri [...] | Transmembrane protein 185A; Belongs to the TMEM185 family. | 0.955 |
| ATP6V0D2 | ATP6V0D1 | ENSP00000285393 | ENSP00000290949 | V-type proton ATPase subunit d 2; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity). | V-type proton ATPase subunit d 1; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity). May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity). In aerobic conditions, involved in intracellular iron homeostasis, thus tri [...] | 0.999 |
| ATP6V0D2 | TMEM185A | ENSP00000285393 | ENSP00000471932 | V-type proton ATPase subunit d 2; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity). | Transmembrane protein 185A; Belongs to the TMEM185 family. | 0.980 |
| C1orf21 | TMEM185A | ENSP00000235307 | ENSP00000471932 | Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21. | Transmembrane protein 185A; Belongs to the TMEM185 family. | 0.775 |
| CPNE8 | TMEM185A | ENSP00000329748 | ENSP00000471932 | Copine-8; Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes. Belongs to the copine family. | Transmembrane protein 185A; Belongs to the TMEM185 family. | 0.731 |
| CSNK1G1 | TMEM185A | ENSP00000475724 | ENSP00000471932 | Casein kinase I isoform gamma-1; Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity). Phosphorylates CLSPN. | Transmembrane protein 185A; Belongs to the TMEM185 family. | 0.844 |
| FMR1 | AFF2 | ENSP00000359506 | ENSP00000359489 | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export (By similarity). Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons (By similarity). Stabilizes the scaffolding postsyna [...] | AF4/FMR2 family member 2; RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure. | 0.940 |
| FMR1 | TMEM185A | ENSP00000359506 | ENSP00000471932 | Synaptic functional regulator FMR1; Multifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs. Plays a role in the alternative splicing of its own mRNA. Plays a role in mRNA nuclear export (By similarity). Together with export factor NXF2, is involved in the regulation of the NXF1 mRNA stability in neurons (By similarity). Stabilizes the scaffolding postsyna [...] | Transmembrane protein 185A; Belongs to the TMEM185 family. | 0.886 |
| FRA10AC1 | AFF2 | ENSP00000360488 | ENSP00000359489 | Protein FRA10AC1; FRA10A associated CGG repeat 1. | AF4/FMR2 family member 2; RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure. | 0.500 |
| FRA10AC1 | TMEM185A | ENSP00000360488 | ENSP00000471932 | Protein FRA10AC1; FRA10A associated CGG repeat 1. | Transmembrane protein 185A; Belongs to the TMEM185 family. | 0.655 |
| OSTF1 | TMEM185A | ENSP00000340836 | ENSP00000471932 | Osteoclast-stimulating factor 1; Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity. | Transmembrane protein 185A; Belongs to the TMEM185 family. | 0.657 |
| TMEM185A | AFF2 | ENSP00000471932 | ENSP00000359489 | Transmembrane protein 185A; Belongs to the TMEM185 family. | AF4/FMR2 family member 2; RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure. | 0.948 |
| TMEM185A | ATP6V0D1 | ENSP00000471932 | ENSP00000290949 | Transmembrane protein 185A; Belongs to the TMEM185 family. | V-type proton ATPase subunit d 1; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity). May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity). In aerobic conditions, involved in intracellular iron homeostasis, thus tri [...] | 0.955 |
| TMEM185A | ATP6V0D2 | ENSP00000471932 | ENSP00000285393 | Transmembrane protein 185A; Belongs to the TMEM185 family. | V-type proton ATPase subunit d 2; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity). | 0.980 |
| TMEM185A | C1orf21 | ENSP00000471932 | ENSP00000235307 | Transmembrane protein 185A; Belongs to the TMEM185 family. | Uncharacterized protein C1orf21; Chromosome 1 open reading frame 21. | 0.775 |
| TMEM185A | CPNE8 | ENSP00000471932 | ENSP00000329748 | Transmembrane protein 185A; Belongs to the TMEM185 family. | Copine-8; Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes. Belongs to the copine family. | 0.731 |