node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DMBT1 | ZNF320 | ENSP00000357905 | ENSP00000473091 | Deleted in malignant brain tumors 1 protein; May be considered as a candidate tumor suppressor gene for brain, lung, esophageal, gastric, and colorectal cancers. May play roles in mucosal defense system, cellular immune defense and epithelial differentiation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lin [...] | Zinc finger protein 320; May be involved in transcriptional regulation. | 0.825 |
EIF2S3B | LGALS16 | ENSP00000323063 | ENSP00000375904 | Eukaryotic translation initiation factor 2 subunit gamma B. | Galectin-16; Binds lactose with high affinity. Strong inducer of T-cell apoptosis. | 0.437 |
EIF2S3B | ZNF320 | ENSP00000323063 | ENSP00000473091 | Eukaryotic translation initiation factor 2 subunit gamma B. | Zinc finger protein 320; May be involved in transcriptional regulation. | 0.435 |
LGALS16 | EIF2S3B | ENSP00000375904 | ENSP00000323063 | Galectin-16; Binds lactose with high affinity. Strong inducer of T-cell apoptosis. | Eukaryotic translation initiation factor 2 subunit gamma B. | 0.437 |
LGALS16 | ZNF320 | ENSP00000375904 | ENSP00000473091 | Galectin-16; Binds lactose with high affinity. Strong inducer of T-cell apoptosis. | Zinc finger protein 320; May be involved in transcriptional regulation. | 0.436 |
PLAC8L1 | ZNF320 | ENSP00000309087 | ENSP00000473091 | PLAC8-like protein 1; PLAC8 like 1; Belongs to the cornifelin family. | Zinc finger protein 320; May be involved in transcriptional regulation. | 0.447 |
TRIM28 | ZNF320 | ENSP00000253024 | ENSP00000473091 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 320; May be involved in transcriptional regulation. | 0.630 |
TRIM28 | ZNF347 | ENSP00000253024 | ENSP00000405218 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 347; May be involved in transcriptional regulation. | 0.522 |
TRIM28 | ZNF468 | ENSP00000253024 | ENSP00000470381 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 468; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.668 |
TRIM28 | ZNF506 | ENSP00000253024 | ENSP00000393835 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 506; May be involved in transcriptional regulation. | 0.556 |
TRIM28 | ZNF600 | ENSP00000253024 | ENSP00000344791 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 600; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.593 |
ZNF320 | DMBT1 | ENSP00000473091 | ENSP00000357905 | Zinc finger protein 320; May be involved in transcriptional regulation. | Deleted in malignant brain tumors 1 protein; May be considered as a candidate tumor suppressor gene for brain, lung, esophageal, gastric, and colorectal cancers. May play roles in mucosal defense system, cellular immune defense and epithelial differentiation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lin [...] | 0.825 |
ZNF320 | EIF2S3B | ENSP00000473091 | ENSP00000323063 | Zinc finger protein 320; May be involved in transcriptional regulation. | Eukaryotic translation initiation factor 2 subunit gamma B. | 0.435 |
ZNF320 | LGALS16 | ENSP00000473091 | ENSP00000375904 | Zinc finger protein 320; May be involved in transcriptional regulation. | Galectin-16; Binds lactose with high affinity. Strong inducer of T-cell apoptosis. | 0.436 |
ZNF320 | PLAC8L1 | ENSP00000473091 | ENSP00000309087 | Zinc finger protein 320; May be involved in transcriptional regulation. | PLAC8-like protein 1; PLAC8 like 1; Belongs to the cornifelin family. | 0.447 |
ZNF320 | TRIM28 | ENSP00000473091 | ENSP00000253024 | Zinc finger protein 320; May be involved in transcriptional regulation. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.630 |
ZNF320 | ZNF347 | ENSP00000473091 | ENSP00000405218 | Zinc finger protein 320; May be involved in transcriptional regulation. | Zinc finger protein 347; May be involved in transcriptional regulation. | 0.492 |
ZNF320 | ZNF468 | ENSP00000473091 | ENSP00000470381 | Zinc finger protein 320; May be involved in transcriptional regulation. | Zinc finger protein 468; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.772 |
ZNF320 | ZNF506 | ENSP00000473091 | ENSP00000393835 | Zinc finger protein 320; May be involved in transcriptional regulation. | Zinc finger protein 506; May be involved in transcriptional regulation. | 0.423 |
ZNF320 | ZNF600 | ENSP00000473091 | ENSP00000344791 | Zinc finger protein 320; May be involved in transcriptional regulation. | Zinc finger protein 600; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.553 |