ZBTB8B protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACSF2	ZBTB8B	ENSP00000401831	ENSP00000476499	Medium-chain acyl-CoA ligase ACSF2, mitochondrial; Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipocyte differentiation.	Zinc finger and BTB domain-containing protein 8B; May be involved in transcriptional regulation.	0.459
DHX32	GRIFIN	ENSP00000284690	ENSP00000481185	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32; DEAH-box helicase 32; Belongs to the DEAD box helicase family. DEAH subfamily.	Grifin; Galectin-related inter-fiber protein.	0.452
DHX32	ZBTB8B	ENSP00000284690	ENSP00000476499	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32; DEAH-box helicase 32; Belongs to the DEAD box helicase family. DEAH subfamily.	Zinc finger and BTB domain-containing protein 8B; May be involved in transcriptional regulation.	0.425
GRIFIN	DHX32	ENSP00000481185	ENSP00000284690	Grifin; Galectin-related inter-fiber protein.	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32; DEAH-box helicase 32; Belongs to the DEAD box helicase family. DEAH subfamily.	0.452
GRIFIN	MBOAT1	ENSP00000481185	ENSP00000324944	Grifin; Galectin-related inter-fiber protein.	Lysophospholipid acyltransferase 1; Acyltransferase which mediates the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L- serine or PS) (LPSAT activity). Prefers oleoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.	0.472
GRIFIN	ZBTB8B	ENSP00000481185	ENSP00000476499	Grifin; Galectin-related inter-fiber protein.	Zinc finger and BTB domain-containing protein 8B; May be involved in transcriptional regulation.	0.469
MBOAT1	GRIFIN	ENSP00000324944	ENSP00000481185	Lysophospholipid acyltransferase 1; Acyltransferase which mediates the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L- serine or PS) (LPSAT activity). Prefers oleoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.	Grifin; Galectin-related inter-fiber protein.	0.472
MBOAT1	ZBTB8B	ENSP00000324944	ENSP00000476499	Lysophospholipid acyltransferase 1; Acyltransferase which mediates the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L- serine or PS) (LPSAT activity). Prefers oleoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.	Zinc finger and BTB domain-containing protein 8B; May be involved in transcriptional regulation.	0.421
MOCS2	ZBTB8B	ENSP00000380157	ENSP00000476499	Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily.	Zinc finger and BTB domain-containing protein 8B; May be involved in transcriptional regulation.	0.465
ZBTB8B	ACSF2	ENSP00000476499	ENSP00000401831	Zinc finger and BTB domain-containing protein 8B; May be involved in transcriptional regulation.	Medium-chain acyl-CoA ligase ACSF2, mitochondrial; Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipocyte differentiation.	0.459
ZBTB8B	DHX32	ENSP00000476499	ENSP00000284690	Zinc finger and BTB domain-containing protein 8B; May be involved in transcriptional regulation.	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32; DEAH-box helicase 32; Belongs to the DEAD box helicase family. DEAH subfamily.	0.425
ZBTB8B	GRIFIN	ENSP00000476499	ENSP00000481185	Zinc finger and BTB domain-containing protein 8B; May be involved in transcriptional regulation.	Grifin; Galectin-related inter-fiber protein.	0.469
ZBTB8B	MBOAT1	ENSP00000476499	ENSP00000324944	Zinc finger and BTB domain-containing protein 8B; May be involved in transcriptional regulation.	Lysophospholipid acyltransferase 1; Acyltransferase which mediates the conversion of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3-phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn-glycero-3-phospho-L- serine or PS) (LPSAT activity). Prefers oleoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.	0.421
ZBTB8B	MOCS2	ENSP00000476499	ENSP00000380157	Zinc finger and BTB domain-containing protein 8B; May be involved in transcriptional regulation.	Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily.	0.465
ZBTB8B	ZBTB8OS	ENSP00000476499	ENSP00000417677	Zinc finger and BTB domain-containing protein 8B; May be involved in transcriptional regulation.	Protein archease; Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RTCB. Together with DDX1, acts by facilitating the guanylylation of RTCB, a key intermediate step in tRNA ligation; Belongs to the archease family.	0.497
ZBTB8OS	ZBTB8B	ENSP00000417677	ENSP00000476499	Protein archease; Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RTCB. Together with DDX1, acts by facilitating the guanylylation of RTCB, a key intermediate step in tRNA ligation; Belongs to the archease family.	Zinc finger and BTB domain-containing protein 8B; May be involved in transcriptional regulation.	0.497