LOC107987373 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC107987373	MRPL17	ENSP00000478035	ENSP00000288937	39S ribosomal protein L23, mitochondrial.	Mitochondrial ribosomal protein L17.	0.976
LOC107987373	MRPL19	ENSP00000478035	ENSP00000377486	39S ribosomal protein L23, mitochondrial.	Mitochondrial ribosomal protein L19.	0.965
LOC107987373	MRPL24	ENSP00000478035	ENSP00000354525	39S ribosomal protein L23, mitochondrial.	Mitochondrial ribosomal protein L24; Belongs to the universal ribosomal protein uL24 family.	0.962
LOC107987373	MRPL41	ENSP00000478035	ENSP00000360498	39S ribosomal protein L23, mitochondrial.	39S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins.	0.987
LOC107987373	MRPL43	ENSP00000478035	ENSP00000339844	39S ribosomal protein L23, mitochondrial.	Mitochondrial ribosomal protein L43.	0.954
LOC107987373	MRPL45	ENSP00000478035	ENSP00000484903	39S ribosomal protein L23, mitochondrial.	Mitochondrial ribosomal protein L45.	0.946
LOC107987373	MRPL46	ENSP00000478035	ENSP00000312311	39S ribosomal protein L23, mitochondrial.	Mitochondrial ribosomal protein L46; Belongs to the mitochondrion-specific ribosomal protein mL46 family.	0.951
LOC107987373	MRPL47	ENSP00000478035	ENSP00000417602	39S ribosomal protein L23, mitochondrial.	Mitochondrial ribosomal protein L47; Belongs to the universal ribosomal protein uL29 family.	0.969
LOC107987373	MRPL49	ENSP00000478035	ENSP00000279242	39S ribosomal protein L23, mitochondrial.	Mitochondrial ribosomal protein L49.	0.956
LOC107987373	MRPS16	ENSP00000478035	ENSP00000362036	39S ribosomal protein L23, mitochondrial.	Mitochondrial ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.	0.965
MRPL17	LOC107987373	ENSP00000288937	ENSP00000478035	Mitochondrial ribosomal protein L17.	39S ribosomal protein L23, mitochondrial.	0.976
MRPL17	MRPL19	ENSP00000288937	ENSP00000377486	Mitochondrial ribosomal protein L17.	Mitochondrial ribosomal protein L19.	0.999
MRPL17	MRPL24	ENSP00000288937	ENSP00000354525	Mitochondrial ribosomal protein L17.	Mitochondrial ribosomal protein L24; Belongs to the universal ribosomal protein uL24 family.	0.997
MRPL17	MRPL41	ENSP00000288937	ENSP00000360498	Mitochondrial ribosomal protein L17.	39S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins.	0.998
MRPL17	MRPL43	ENSP00000288937	ENSP00000339844	Mitochondrial ribosomal protein L17.	Mitochondrial ribosomal protein L43.	0.986
MRPL17	MRPL45	ENSP00000288937	ENSP00000484903	Mitochondrial ribosomal protein L17.	Mitochondrial ribosomal protein L45.	0.929
MRPL17	MRPL46	ENSP00000288937	ENSP00000312311	Mitochondrial ribosomal protein L17.	Mitochondrial ribosomal protein L46; Belongs to the mitochondrion-specific ribosomal protein mL46 family.	0.991
MRPL17	MRPL47	ENSP00000288937	ENSP00000417602	Mitochondrial ribosomal protein L17.	Mitochondrial ribosomal protein L47; Belongs to the universal ribosomal protein uL29 family.	0.999
MRPL17	MRPL49	ENSP00000288937	ENSP00000279242	Mitochondrial ribosomal protein L17.	Mitochondrial ribosomal protein L49.	0.987
MRPL17	MRPS16	ENSP00000288937	ENSP00000362036	Mitochondrial ribosomal protein L17.	Mitochondrial ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.	0.998