node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDCP2 | FOXI3 | ENSP00000489959 | ENSP00000478384 | CUB domain containing protein 2. | Forkhead box protein I3; Possible transcriptional factor. | 0.428 |
EYA2 | FOXI3 | ENSP00000333640 | ENSP00000478384 | Eyes absent homolog 2; Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription regulat [...] | Forkhead box protein I3; Possible transcriptional factor. | 0.415 |
FOXI3 | CDCP2 | ENSP00000478384 | ENSP00000489959 | Forkhead box protein I3; Possible transcriptional factor. | CUB domain containing protein 2. | 0.428 |
FOXI3 | EYA2 | ENSP00000478384 | ENSP00000333640 | Forkhead box protein I3; Possible transcriptional factor. | Eyes absent homolog 2; Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription regulat [...] | 0.415 |
FOXI3 | GCM2 | ENSP00000478384 | ENSP00000368805 | Forkhead box protein I3; Possible transcriptional factor. | Chorion-specific transcription factor GCMb; Transcription factor that binds specific sequences on gene promoters and activate their transcription. Through the regulation of gene transcription, may play a role in parathyroid gland development. | 0.626 |
FOXI3 | KRCC1 | ENSP00000478384 | ENSP00000340083 | Forkhead box protein I3; Possible transcriptional factor. | Lysine rich coiled-coil 1. | 0.400 |
FOXI3 | KRT71 | ENSP00000478384 | ENSP00000267119 | Forkhead box protein I3; Possible transcriptional factor. | Keratin, type II cytoskeletal 71; Plays a central role in hair formation. Essential component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle. | 0.457 |
FOXI3 | TEX37 | ENSP00000478384 | ENSP00000307142 | Forkhead box protein I3; Possible transcriptional factor. | Testis-expressed sequence 37 protein; Testis expressed 37. | 0.515 |
FOXI3 | THNSL2 | ENSP00000478384 | ENSP00000327323 | Forkhead box protein I3; Possible transcriptional factor. | Threonine synthase-like 2; [Isoform 1]: Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates. Degrades O-phospho-threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate (By similarity). | 0.512 |
GCM2 | FOXI3 | ENSP00000368805 | ENSP00000478384 | Chorion-specific transcription factor GCMb; Transcription factor that binds specific sequences on gene promoters and activate their transcription. Through the regulation of gene transcription, may play a role in parathyroid gland development. | Forkhead box protein I3; Possible transcriptional factor. | 0.626 |
KRCC1 | FOXI3 | ENSP00000340083 | ENSP00000478384 | Lysine rich coiled-coil 1. | Forkhead box protein I3; Possible transcriptional factor. | 0.400 |
KRCC1 | TEX37 | ENSP00000340083 | ENSP00000307142 | Lysine rich coiled-coil 1. | Testis-expressed sequence 37 protein; Testis expressed 37. | 0.404 |
KRCC1 | THNSL2 | ENSP00000340083 | ENSP00000327323 | Lysine rich coiled-coil 1. | Threonine synthase-like 2; [Isoform 1]: Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates. Degrades O-phospho-threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate (By similarity). | 0.420 |
KRT71 | FOXI3 | ENSP00000267119 | ENSP00000478384 | Keratin, type II cytoskeletal 71; Plays a central role in hair formation. Essential component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle. | Forkhead box protein I3; Possible transcriptional factor. | 0.457 |
TEX37 | FOXI3 | ENSP00000307142 | ENSP00000478384 | Testis-expressed sequence 37 protein; Testis expressed 37. | Forkhead box protein I3; Possible transcriptional factor. | 0.515 |
TEX37 | KRCC1 | ENSP00000307142 | ENSP00000340083 | Testis-expressed sequence 37 protein; Testis expressed 37. | Lysine rich coiled-coil 1. | 0.404 |
TEX37 | THNSL2 | ENSP00000307142 | ENSP00000327323 | Testis-expressed sequence 37 protein; Testis expressed 37. | Threonine synthase-like 2; [Isoform 1]: Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates. Degrades O-phospho-threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate (By similarity). | 0.568 |
THNSL2 | FOXI3 | ENSP00000327323 | ENSP00000478384 | Threonine synthase-like 2; [Isoform 1]: Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates. Degrades O-phospho-threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate (By similarity). | Forkhead box protein I3; Possible transcriptional factor. | 0.512 |
THNSL2 | KRCC1 | ENSP00000327323 | ENSP00000340083 | Threonine synthase-like 2; [Isoform 1]: Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates. Degrades O-phospho-threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate (By similarity). | Lysine rich coiled-coil 1. | 0.420 |
THNSL2 | TEX37 | ENSP00000327323 | ENSP00000307142 | Threonine synthase-like 2; [Isoform 1]: Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates. Degrades O-phospho-threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate (By similarity). | Testis-expressed sequence 37 protein; Testis expressed 37. | 0.568 |