NATD1 protein (human) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAMTSL4	NATD1	ENSP00000358035	ENSP00000478388	ADAMTS-like protein 4; Positive regulation of apoptosis. May facilitate FBN1 microfibril biogenesis.	Protein NATD1; N-acetyltransferase domain containing 1.	0.477
ARMC8	GID8	ENSP00000419413	ENSP00000266069	Armadillo repeat-containing protein 8; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.	Glucose-induced degradation protein 8 homolog; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Acts as a positive regulator of Wnt signaling pathway by promoting beta-catenin (CTNNB1) nuclear accumulation ; Belongs to the GID8 family.	0.999
ARMC8	NATD1	ENSP00000419413	ENSP00000478388	Armadillo repeat-containing protein 8; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.	Protein NATD1; N-acetyltransferase domain containing 1.	0.449
ARMC8	UBE2H	ENSP00000419413	ENSP00000347836	Armadillo repeat-containing protein 8; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.	Ubiquitin-conjugating enzyme E2 H; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. E2 ubiquitin conjugating enzyme that transfers ubiquitin to MAEA, a core component of the CTLH E3 ubiquitin-protein ligase complex. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Capable, in vitro, to ubiquitinate histone H2A.	0.968
FAM229B	GASK1A	ENSP00000357645	ENSP00000407301	Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family.	Golgi associated kinase 1A; Belongs to the GASK family.	0.535
FAM229B	NATD1	ENSP00000357645	ENSP00000478388	Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family.	Protein NATD1; N-acetyltransferase domain containing 1.	0.466
GASK1A	FAM229B	ENSP00000407301	ENSP00000357645	Golgi associated kinase 1A; Belongs to the GASK family.	Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family.	0.535
GASK1A	NATD1	ENSP00000407301	ENSP00000478388	Golgi associated kinase 1A; Belongs to the GASK family.	Protein NATD1; N-acetyltransferase domain containing 1.	0.400
GID8	ARMC8	ENSP00000266069	ENSP00000419413	Glucose-induced degradation protein 8 homolog; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Acts as a positive regulator of Wnt signaling pathway by promoting beta-catenin (CTNNB1) nuclear accumulation ; Belongs to the GID8 family.	Armadillo repeat-containing protein 8; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.	0.999
GID8	NATD1	ENSP00000266069	ENSP00000478388	Glucose-induced degradation protein 8 homolog; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Acts as a positive regulator of Wnt signaling pathway by promoting beta-catenin (CTNNB1) nuclear accumulation ; Belongs to the GID8 family.	Protein NATD1; N-acetyltransferase domain containing 1.	0.663
GID8	UBE2H	ENSP00000266069	ENSP00000347836	Glucose-induced degradation protein 8 homolog; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Acts as a positive regulator of Wnt signaling pathway by promoting beta-catenin (CTNNB1) nuclear accumulation ; Belongs to the GID8 family.	Ubiquitin-conjugating enzyme E2 H; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. E2 ubiquitin conjugating enzyme that transfers ubiquitin to MAEA, a core component of the CTLH E3 ubiquitin-protein ligase complex. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Capable, in vitro, to ubiquitinate histone H2A.	0.927
NATD1	ADAMTSL4	ENSP00000478388	ENSP00000358035	Protein NATD1; N-acetyltransferase domain containing 1.	ADAMTS-like protein 4; Positive regulation of apoptosis. May facilitate FBN1 microfibril biogenesis.	0.477
NATD1	ARMC8	ENSP00000478388	ENSP00000419413	Protein NATD1; N-acetyltransferase domain containing 1.	Armadillo repeat-containing protein 8; Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.	0.449
NATD1	FAM229B	ENSP00000478388	ENSP00000357645	Protein NATD1; N-acetyltransferase domain containing 1.	Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family.	0.466
NATD1	GASK1A	ENSP00000478388	ENSP00000407301	Protein NATD1; N-acetyltransferase domain containing 1.	Golgi associated kinase 1A; Belongs to the GASK family.	0.400
NATD1	GID8	ENSP00000478388	ENSP00000266069	Protein NATD1; N-acetyltransferase domain containing 1.	Glucose-induced degradation protein 8 homolog; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Acts as a positive regulator of Wnt signaling pathway by promoting beta-catenin (CTNNB1) nuclear accumulation ; Belongs to the GID8 family.	0.663
NATD1	PJA1	ENSP00000478388	ENSP00000355014	Protein NATD1; N-acetyltransferase domain containing 1.	E3 ubiquitin-protein ligase Praja-1; Has E2-dependent E3 ubiquitin-protein ligase activity. Ubiquitinates MAGED1 antigen leading to its subsequent degradation by proteasome (By similarity). May be involved in protein sorting.	0.457
NATD1	STRA8	ENSP00000478388	ENSP00000275764	Protein NATD1; N-acetyltransferase domain containing 1.	Stimulated by retinoic acid gene 8 protein homolog; Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. Can associate with DNA (possibly in an indirect manner), and in vitro can activate DNA transcription (By similarity).	0.441
NATD1	TMEM11	ENSP00000478388	ENSP00000319992	Protein NATD1; N-acetyltransferase domain containing 1.	Transmembrane protein 11, mitochondrial; Plays a role in mitochondrial morphogenesis. Belongs to the TMEM11 family.	0.421
NATD1	UBE2H	ENSP00000478388	ENSP00000347836	Protein NATD1; N-acetyltransferase domain containing 1.	Ubiquitin-conjugating enzyme E2 H; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. E2 ubiquitin conjugating enzyme that transfers ubiquitin to MAEA, a core component of the CTLH E3 ubiquitin-protein ligase complex. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Capable, in vitro, to ubiquitinate histone H2A.	0.476