STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PINLYPPhospholipase A2 inhibitor and LY6/PLAUR domain containing; Belongs to the CNF-like-inhibitor family. (228 aa)    
Predicted Functional Partners:
LYPD5
LY6/PLAUR domain containing 5.
   
  
 0.730
LY6L
Lymphocyte antigen 6 family member L.
      
 0.717
PATE3
Prostate and testis expressed 3; Belongs to the PATE family.
      
 0.697
PATE2
Prostate and testis expressed 2.
   
  
 0.646
PATE1
Prostate and testis expressed 1; Belongs to the PATE family.
      
 0.620
LY6G5B
Lymphocyte antigen 6 family member G5B.
      
 0.599
PATE4
Prostate and testis expressed protein 4; May modulate the function of nicotinic acetylcholine receptors. May enhance sperm motility.
   
  
 0.594
LYPD3
Ly6/PLAUR domain-containing protein 3; Supports cell migration. May be involved in urothelial cell- matrix interactions. May be involved in tumor progression.
   
  
 0.589
LYPD4
LY6/PLAUR domain containing 4.
      
 0.585
TEX101
Testis-expressed protein 101; Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct (By similarity). May play a role in signal transduction and promote protein tyrosine phosphorylation (By similarity).
      
 0.582
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.