LRCOL1 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C7orf31	CABS1	ENSP00000283905	ENSP00000273936	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	Calcium-binding and spermatid-specific protein 1; Calcium binding protein, spermatid associated 1.	0.485
C7orf31	EDDM3B	ENSP00000283905	ENSP00000314810	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	Epididymal secretory protein E3-beta; Possible function in sperm maturation.	0.497
C7orf31	FAM229B	ENSP00000283905	ENSP00000357645	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family.	0.565
C7orf31	FSCB	ENSP00000283905	ENSP00000344579	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	Fibrous sheath CABYR-binding protein; May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium.	0.470
C7orf31	LRCOL1	ENSP00000283905	ENSP00000479730	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	Leucine-rich colipase-like protein 1; Leucine rich colipase like 1.	0.654
C7orf31	SPATA24	ENSP00000283905	ENSP00000414920	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	Spermatogenesis-associated protein 24; Binds DNA with high affinity but does not bind to TATA boxes. Synergises with GMNN and TBP in activation of TATA box-containing promoters and with GMNN and TBPL1 in activation of the NF1 TATA-less promoter. May play a role in cytoplasm movement and removal during spermiogenesis (By similarity).	0.460
CABS1	C7orf31	ENSP00000273936	ENSP00000283905	Calcium-binding and spermatid-specific protein 1; Calcium binding protein, spermatid associated 1.	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	0.485
CABS1	LRCOL1	ENSP00000273936	ENSP00000479730	Calcium-binding and spermatid-specific protein 1; Calcium binding protein, spermatid associated 1.	Leucine-rich colipase-like protein 1; Leucine rich colipase like 1.	0.450
EDDM3B	C7orf31	ENSP00000314810	ENSP00000283905	Epididymal secretory protein E3-beta; Possible function in sperm maturation.	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	0.497
EDDM3B	LRCOL1	ENSP00000314810	ENSP00000479730	Epididymal secretory protein E3-beta; Possible function in sperm maturation.	Leucine-rich colipase-like protein 1; Leucine rich colipase like 1.	0.491
FAM229B	C7orf31	ENSP00000357645	ENSP00000283905	Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family.	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	0.565
FAM229B	FSCB	ENSP00000357645	ENSP00000344579	Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family.	Fibrous sheath CABYR-binding protein; May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium.	0.425
FAM229B	LRCOL1	ENSP00000357645	ENSP00000479730	Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family.	Leucine-rich colipase-like protein 1; Leucine rich colipase like 1.	0.596
FAM229B	SPATA24	ENSP00000357645	ENSP00000414920	Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family.	Spermatogenesis-associated protein 24; Binds DNA with high affinity but does not bind to TATA boxes. Synergises with GMNN and TBP in activation of TATA box-containing promoters and with GMNN and TBPL1 in activation of the NF1 TATA-less promoter. May play a role in cytoplasm movement and removal during spermiogenesis (By similarity).	0.517
FSCB	C7orf31	ENSP00000344579	ENSP00000283905	Fibrous sheath CABYR-binding protein; May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium.	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	0.470
FSCB	FAM229B	ENSP00000344579	ENSP00000357645	Fibrous sheath CABYR-binding protein; May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium.	Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family.	0.425
FSCB	LRCOL1	ENSP00000344579	ENSP00000479730	Fibrous sheath CABYR-binding protein; May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium.	Leucine-rich colipase-like protein 1; Leucine rich colipase like 1.	0.483
H7C0V5_HUMAN	LRCOL1	ENSP00000432016	ENSP00000479730	ANKHD1-EIF4EBP3 readthrough.	Leucine-rich colipase-like protein 1; Leucine rich colipase like 1.	0.520
LRCOL1	C7orf31	ENSP00000479730	ENSP00000283905	Leucine-rich colipase-like protein 1; Leucine rich colipase like 1.	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	0.654
LRCOL1	CABS1	ENSP00000479730	ENSP00000273936	Leucine-rich colipase-like protein 1; Leucine rich colipase like 1.	Calcium-binding and spermatid-specific protein 1; Calcium binding protein, spermatid associated 1.	0.450