STRINGSTRING
PRSS56 protein (human) - STRING interaction network
"PRSS56" - Serine protease 56 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
PRSS56Serine protease 56; Serine protease required during eye development (603 aa)    
Predicted Functional Partners:
ENSG00000259159
Membrane frizzled-related protein; May play a role in eye development; C1q and TNF related (579 aa)
           
  0.796
ENSG00000235718
Membrane frizzled-related protein; May play a role in eye development (579 aa)
           
  0.796
SHISA6
Protein shisa-6 homolog; Shisa family member 6 (551 aa)
           
  0.741
KCNQ5
Potassium voltage-gated channel subfamily KQT member 5; Associates with KCNQ3 to form a potassium channel which contributes to M-type current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons. Therefore, it is important in the regulation of neuronal excitability. May contribute, with other potassium channels, to the molecular diversity of a heterogeneous population of M- channels, varying in kinetic and pharmacological properties, which underlie this physiologically important curren [...] (951 aa)
           
  0.644
RDH5
11-cis retinol dehydrogenase; Stereospecific 11-cis retinol dehydrogenase, which catalyzes the final step in the biosynthesis of 11-cis retinaldehyde, the universal chromophore of visual pigments. Also able to oxidize 9-cis-retinol and 13-cis-retinol, but not all- trans-retinol. Active in the presence of NAD as cofactor but not in the presence of NADP; Short chain dehydrogenase/reductase superfamily (318 aa)
       
 
  0.641
LAMA2
Laminin subunit alpha-2; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components (3122 aa)
           
  0.586
TCTE1
T-complex-associated-testis-expressed 1; Dynein regulatory complex (501 aa)
       
 
  0.569
GJD2
Gap junction delta-2 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell; Belongs to the connexin family. Delta-type subfamily (321 aa)
           
  0.557
ZMAT4
Zinc finger matrin-type 4 (229 aa)
           
  0.555
SIX6
Homeobox protein SIX6; May be involved in eye development; SINE class homeoboxes (246 aa)
           
  0.549
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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