Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SLC22A24Steroid transmembrane transporter SLC22A24; Steroid transmembrane transporter that functions in the reabsorption of conjugated steroids in the kidney and is involved in steroid homeostasis. [Isoform 3]: Lack of transporter activity. (552 aa)    
Predicted Functional Partners:
OR7G3
Olfactory receptor 7G3; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.626
FAM187B
Protein FAM187B; Family with sequence similarity 187 member B.
   
  
 0.615
OR5AR1
Olfactory receptor 5AR1; Odorant receptor.
   
  
 0.597
MAGEB16
Melanoma-associated antigen B16; MAGE family member B16.
    
 
 0.541
SLC22A18
Solute carrier family 22 member 18; May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney. Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
   
 
 0.539
CBY2
Chibby family member 2.
   
  
 0.536
SLC22A15
Solute carrier family 22 member 15; Probably transports organic cations (By similarity). Appears not to be the agmatine transporter.
  
   
0.515
SLC16A5
Monocarboxylate transporter 6; Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity); Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
   
  
 0.472
ZNF80
Zinc finger protein 80; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
      
 0.469
ABCA10
ATP-binding cassette sub-family A member 10; Probable transporter which may play a role in macrophage lipid homeostasis.
   
 
 0.468
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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