node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANTXRL | CHST9 | ENSP00000480615 | ENSP00000480991 | Anthrax toxin receptor like | Carbohydrate sulfotransferase 9; Catalyzes the transfer of sulfate to position 4 of non- reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Participates in biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Has a higher activity toward carbonic anhydrase VI than toward lutropin. Only active against terminal GalNAcbeta1,GalNAcbeta. Isoform 2, but not isoform 1, is active toward chondroitin; Sulfotransferases, membrane bound | 0.556 |
ANTXRL | CTIF | ENSP00000480615 | ENSP00000372459 | Anthrax toxin receptor like | CBP80/20-dependent translation initiation factor; Specifically required for the pioneer round of mRNA translation mediated by the cap-binding complex (CBC), that takes place during or right after mRNA export via the nuclear pore complex (NPC). Acts via its interaction with the NCBP1/CBP80 component of the CBC complex and recruits the 40S small subunit of the ribosome via eIF3. In contrast, it is not involved in steady state translation, that takes place when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. Also required for nonsense-mediated mRNA decay (NMD), the p [...] | 0.550 |
ANTXRL | EML6 | ENSP00000480615 | ENSP00000348842 | Anthrax toxin receptor like | Echinoderm microtubule-associated protein-like 6; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic; WD repeat domain containing | 0.709 |
ANTXRL | MTCL1 | ENSP00000480615 | ENSP00000352927 | Anthrax toxin receptor like | Microtubule cross-linking factor 1; Microtubule-associated factor involved in the late phase of epithelial polarization and microtubule dynamics regulation. Plays a role in the development and maintenance of non-centrosomal microtubule bundles at the lateral membrane in polarized epithelial cells; Belongs to the SOGA family | 0.695 |
ANTXRL | NKAIN2 | ENSP00000480615 | ENSP00000357402 | Anthrax toxin receptor like | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2; Sodium/potassium transporting ATPase interacting 2 | 0.575 |
ANTXRL | SEPSECS | ENSP00000480615 | ENSP00000371535 | Anthrax toxin receptor like | O-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis | 0.562 |
ANTXRL | TRIM59 | ENSP00000480615 | ENSP00000311219 | Anthrax toxin receptor like | Tripartite motif-containing protein 59; May serve as a multifunctional regulator for innate immune signaling pathways; Ring finger proteins | 0.531 |
ANTXRL | TSEN2 | ENSP00000480615 | ENSP00000284995 | Anthrax toxin receptor like | tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] | 0.596 |
ANTXRL | ZNF813 | ENSP00000480615 | ENSP00000379684 | Anthrax toxin receptor like | Zinc finger protein 813; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.656 |
ANTXRL | ZYG11B | ENSP00000480615 | ENSP00000294353 | Anthrax toxin receptor like | Protein zyg-11 homolog B; Probably acts as target recruitment subunit in the E3 ubiquitin ligase complex ZYG11B-CUL2-Elongin BC; Armadillo-like helical domain containing | 0.707 |
CHST9 | ANTXRL | ENSP00000480991 | ENSP00000480615 | Carbohydrate sulfotransferase 9; Catalyzes the transfer of sulfate to position 4 of non- reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Participates in biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Has a higher activity toward carbonic anhydrase VI than toward lutropin. Only active against terminal GalNAcbeta1,GalNAcbeta. Isoform 2, but not isoform 1, is active toward chondroitin; Sulfotransferases, membrane bound | Anthrax toxin receptor like | 0.556 |
CTIF | ANTXRL | ENSP00000372459 | ENSP00000480615 | CBP80/20-dependent translation initiation factor; Specifically required for the pioneer round of mRNA translation mediated by the cap-binding complex (CBC), that takes place during or right after mRNA export via the nuclear pore complex (NPC). Acts via its interaction with the NCBP1/CBP80 component of the CBC complex and recruits the 40S small subunit of the ribosome via eIF3. In contrast, it is not involved in steady state translation, that takes place when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. Also required for nonsense-mediated mRNA decay (NMD), the p [...] | Anthrax toxin receptor like | 0.550 |
CTIF | EML6 | ENSP00000372459 | ENSP00000348842 | CBP80/20-dependent translation initiation factor; Specifically required for the pioneer round of mRNA translation mediated by the cap-binding complex (CBC), that takes place during or right after mRNA export via the nuclear pore complex (NPC). Acts via its interaction with the NCBP1/CBP80 component of the CBC complex and recruits the 40S small subunit of the ribosome via eIF3. In contrast, it is not involved in steady state translation, that takes place when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. Also required for nonsense-mediated mRNA decay (NMD), the p [...] | Echinoderm microtubule-associated protein-like 6; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic; WD repeat domain containing | 0.551 |
CTIF | MTCL1 | ENSP00000372459 | ENSP00000352927 | CBP80/20-dependent translation initiation factor; Specifically required for the pioneer round of mRNA translation mediated by the cap-binding complex (CBC), that takes place during or right after mRNA export via the nuclear pore complex (NPC). Acts via its interaction with the NCBP1/CBP80 component of the CBC complex and recruits the 40S small subunit of the ribosome via eIF3. In contrast, it is not involved in steady state translation, that takes place when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. Also required for nonsense-mediated mRNA decay (NMD), the p [...] | Microtubule cross-linking factor 1; Microtubule-associated factor involved in the late phase of epithelial polarization and microtubule dynamics regulation. Plays a role in the development and maintenance of non-centrosomal microtubule bundles at the lateral membrane in polarized epithelial cells; Belongs to the SOGA family | 0.570 |
CTIF | NKAIN2 | ENSP00000372459 | ENSP00000357402 | CBP80/20-dependent translation initiation factor; Specifically required for the pioneer round of mRNA translation mediated by the cap-binding complex (CBC), that takes place during or right after mRNA export via the nuclear pore complex (NPC). Acts via its interaction with the NCBP1/CBP80 component of the CBC complex and recruits the 40S small subunit of the ribosome via eIF3. In contrast, it is not involved in steady state translation, that takes place when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. Also required for nonsense-mediated mRNA decay (NMD), the p [...] | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2; Sodium/potassium transporting ATPase interacting 2 | 0.491 |
EML6 | ANTXRL | ENSP00000348842 | ENSP00000480615 | Echinoderm microtubule-associated protein-like 6; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic; WD repeat domain containing | Anthrax toxin receptor like | 0.709 |
EML6 | CTIF | ENSP00000348842 | ENSP00000372459 | Echinoderm microtubule-associated protein-like 6; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic; WD repeat domain containing | CBP80/20-dependent translation initiation factor; Specifically required for the pioneer round of mRNA translation mediated by the cap-binding complex (CBC), that takes place during or right after mRNA export via the nuclear pore complex (NPC). Acts via its interaction with the NCBP1/CBP80 component of the CBC complex and recruits the 40S small subunit of the ribosome via eIF3. In contrast, it is not involved in steady state translation, that takes place when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. Also required for nonsense-mediated mRNA decay (NMD), the p [...] | 0.551 |
EML6 | MTCL1 | ENSP00000348842 | ENSP00000352927 | Echinoderm microtubule-associated protein-like 6; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic; WD repeat domain containing | Microtubule cross-linking factor 1; Microtubule-associated factor involved in the late phase of epithelial polarization and microtubule dynamics regulation. Plays a role in the development and maintenance of non-centrosomal microtubule bundles at the lateral membrane in polarized epithelial cells; Belongs to the SOGA family | 0.696 |
EML6 | NKAIN2 | ENSP00000348842 | ENSP00000357402 | Echinoderm microtubule-associated protein-like 6; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic; WD repeat domain containing | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2; Sodium/potassium transporting ATPase interacting 2 | 0.455 |
MTCL1 | ANTXRL | ENSP00000352927 | ENSP00000480615 | Microtubule cross-linking factor 1; Microtubule-associated factor involved in the late phase of epithelial polarization and microtubule dynamics regulation. Plays a role in the development and maintenance of non-centrosomal microtubule bundles at the lateral membrane in polarized epithelial cells; Belongs to the SOGA family | Anthrax toxin receptor like | 0.695 |