C18orf32 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C18orf32	ETFRF1	ENSP00000480941	ENSP00000450584	UPF0729 protein C18orf32; May activate the NF-kappa-B signaling pathway.	Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB); Belongs to the complex I LYR family.	0.445
C18orf32	FSTL4	ENSP00000480941	ENSP00000265342	UPF0729 protein C18orf32; May activate the NF-kappa-B signaling pathway.	Follistatin-related protein 4; Follistatin like 4.	0.478
C18orf32	GLP1R	ENSP00000480941	ENSP00000362353	UPF0729 protein C18orf32; May activate the NF-kappa-B signaling pathway.	Glucagon-like peptide 1 receptor; G-protein coupled receptor for glucagon-like peptide 1 (GLP- 1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1 (By similarity).	0.456
C18orf32	RPL17-C18orf32	ENSP00000480941	ENSP00000463379	UPF0729 protein C18orf32; May activate the NF-kappa-B signaling pathway.	RPL17-C18orf32 readthrough; Belongs to the universal ribosomal protein uL22 family.	0.461
C18orf32	SPCS1	ENSP00000480941	ENSP00000233025	UPF0729 protein C18orf32; May activate the NF-kappa-B signaling pathway.	Signal peptidase complex subunit 1; Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Belongs to the SPCS1 family.	0.415
C18orf32	UBAC2	ENSP00000480941	ENSP00000383911	UPF0729 protein C18orf32; May activate the NF-kappa-B signaling pathway.	Ubiquitin-associated domain-containing protein 2; Restricts trafficking of FAF2 from the endoplasmic reticulum to lipid droplets. In association with LMBR1L and E3 ubiquitin-protein ligase AMFR, negatively regulates the canonical Wnt signaling pathway in the lymphocytes by promoting the ubiquitin- mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6.	0.463
ETFRF1	C18orf32	ENSP00000450584	ENSP00000480941	Electron transfer flavoprotein regulatory factor 1; Acts as a regulator of the electron transfer flavoprotein by promoting the removal of flavin from the ETF holoenzyme (composed of ETFA and ETFB); Belongs to the complex I LYR family.	UPF0729 protein C18orf32; May activate the NF-kappa-B signaling pathway.	0.445
FSTL4	C18orf32	ENSP00000265342	ENSP00000480941	Follistatin-related protein 4; Follistatin like 4.	UPF0729 protein C18orf32; May activate the NF-kappa-B signaling pathway.	0.478
GLP1R	C18orf32	ENSP00000362353	ENSP00000480941	Glucagon-like peptide 1 receptor; G-protein coupled receptor for glucagon-like peptide 1 (GLP- 1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1 (By similarity).	UPF0729 protein C18orf32; May activate the NF-kappa-B signaling pathway.	0.456
RPL17-C18orf32	C18orf32	ENSP00000463379	ENSP00000480941	RPL17-C18orf32 readthrough; Belongs to the universal ribosomal protein uL22 family.	UPF0729 protein C18orf32; May activate the NF-kappa-B signaling pathway.	0.461
SPCS1	C18orf32	ENSP00000233025	ENSP00000480941	Signal peptidase complex subunit 1; Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Belongs to the SPCS1 family.	UPF0729 protein C18orf32; May activate the NF-kappa-B signaling pathway.	0.415
UBAC2	C18orf32	ENSP00000383911	ENSP00000480941	Ubiquitin-associated domain-containing protein 2; Restricts trafficking of FAF2 from the endoplasmic reticulum to lipid droplets. In association with LMBR1L and E3 ubiquitin-protein ligase AMFR, negatively regulates the canonical Wnt signaling pathway in the lymphocytes by promoting the ubiquitin- mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6.	UPF0729 protein C18orf32; May activate the NF-kappa-B signaling pathway.	0.463