IQCA1L protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASB10	HHATL	ENSP00000391137	ENSP00000405423	Ankyrin repeat and SOCS box protein 10; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	Protein-cysteine N-palmitoyltransferase HHAT-like protein; Negatively regulates N-terminal palmitoylation of SHH by HHAT/SKN; Belongs to the membrane-bound acyltransferase family. HHAT subfamily.	0.430
ASB10	IQCA1L	ENSP00000391137	ENSP00000482119	Ankyrin repeat and SOCS box protein 10; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	IQ and AAA domain-containing protein 1-like; IQ motif containing with AAA domain 1 like; Belongs to the AAA ATPase family.	0.645
ASB10	TMEM233	ENSP00000391137	ENSP00000403130	Ankyrin repeat and SOCS box protein 10; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	Transmembrane protein 233.	0.401
DUPD1	IQCA1L	ENSP00000340609	ENSP00000482119	Dual specificity phosphatase DUPD1; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	IQ and AAA domain-containing protein 1-like; IQ motif containing with AAA domain 1 like; Belongs to the AAA ATPase family.	0.551
DUPD1	MYADML2	ENSP00000340609	ENSP00000386702	Dual specificity phosphatase DUPD1; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Myeloid-associated differentiation marker-like protein 2; Myeloid associated differentiation marker like 2.	0.450
DUPD1	PHF24	ENSP00000340609	ENSP00000242315	Dual specificity phosphatase DUPD1; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	PHD finger protein 24.	0.401
DUPD1	SBK3	ENSP00000340609	ENSP00000483467	Dual specificity phosphatase DUPD1; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Uncharacterized serine/threonine-protein kinase SBK3; SH3 domain binding kinase family member 3; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. STKL subfamily.	0.446
DUPD1	TMEM233	ENSP00000340609	ENSP00000403130	Dual specificity phosphatase DUPD1; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Transmembrane protein 233.	0.404
FAM189A1	GBX1	ENSP00000261275	ENSP00000297537	Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family.	Homeobox protein GBX-1; Gastrulation brain homeobox 1.	0.461
FAM189A1	IQCA1L	ENSP00000261275	ENSP00000482119	Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family.	IQ and AAA domain-containing protein 1-like; IQ motif containing with AAA domain 1 like; Belongs to the AAA ATPase family.	0.550
GBX1	FAM189A1	ENSP00000297537	ENSP00000261275	Homeobox protein GBX-1; Gastrulation brain homeobox 1.	Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family.	0.461
GBX1	IQCA1L	ENSP00000297537	ENSP00000482119	Homeobox protein GBX-1; Gastrulation brain homeobox 1.	IQ and AAA domain-containing protein 1-like; IQ motif containing with AAA domain 1 like; Belongs to the AAA ATPase family.	0.565
HHATL	ASB10	ENSP00000405423	ENSP00000391137	Protein-cysteine N-palmitoyltransferase HHAT-like protein; Negatively regulates N-terminal palmitoylation of SHH by HHAT/SKN; Belongs to the membrane-bound acyltransferase family. HHAT subfamily.	Ankyrin repeat and SOCS box protein 10; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	0.430
HHATL	IQCA1L	ENSP00000405423	ENSP00000482119	Protein-cysteine N-palmitoyltransferase HHAT-like protein; Negatively regulates N-terminal palmitoylation of SHH by HHAT/SKN; Belongs to the membrane-bound acyltransferase family. HHAT subfamily.	IQ and AAA domain-containing protein 1-like; IQ motif containing with AAA domain 1 like; Belongs to the AAA ATPase family.	0.552
HHATL	MYADML2	ENSP00000405423	ENSP00000386702	Protein-cysteine N-palmitoyltransferase HHAT-like protein; Negatively regulates N-terminal palmitoylation of SHH by HHAT/SKN; Belongs to the membrane-bound acyltransferase family. HHAT subfamily.	Myeloid-associated differentiation marker-like protein 2; Myeloid associated differentiation marker like 2.	0.576
HHATL	PHF24	ENSP00000405423	ENSP00000242315	Protein-cysteine N-palmitoyltransferase HHAT-like protein; Negatively regulates N-terminal palmitoylation of SHH by HHAT/SKN; Belongs to the membrane-bound acyltransferase family. HHAT subfamily.	PHD finger protein 24.	0.484
HHATL	SBK3	ENSP00000405423	ENSP00000483467	Protein-cysteine N-palmitoyltransferase HHAT-like protein; Negatively regulates N-terminal palmitoylation of SHH by HHAT/SKN; Belongs to the membrane-bound acyltransferase family. HHAT subfamily.	Uncharacterized serine/threonine-protein kinase SBK3; SH3 domain binding kinase family member 3; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. STKL subfamily.	0.502
HHATL	TMEM233	ENSP00000405423	ENSP00000403130	Protein-cysteine N-palmitoyltransferase HHAT-like protein; Negatively regulates N-terminal palmitoylation of SHH by HHAT/SKN; Belongs to the membrane-bound acyltransferase family. HHAT subfamily.	Transmembrane protein 233.	0.493
IQCA1L	ASB10	ENSP00000482119	ENSP00000391137	IQ and AAA domain-containing protein 1-like; IQ motif containing with AAA domain 1 like; Belongs to the AAA ATPase family.	Ankyrin repeat and SOCS box protein 10; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	0.645
IQCA1L	DUPD1	ENSP00000482119	ENSP00000340609	IQ and AAA domain-containing protein 1-like; IQ motif containing with AAA domain 1 like; Belongs to the AAA ATPase family.	Dual specificity phosphatase DUPD1; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.551