Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADAMTSL3 | ASTN2 | ENSP00000286744 | ENSP00000354504 | ADAMTS-like protein 3; ADAMTS like 3. | Astrotactin-2; Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (By similarity). Selectively binds inositol-4,5- bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5- tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup. | 0.998 |
| ADAMTSL3 | FAM228B | ENSP00000286744 | ENSP00000482482 | ADAMTS-like protein 3; ADAMTS like 3. | Protein FAM228B; Family with sequence similarity 228 member B; Belongs to the FAM228 family. | 0.493 |
| ADAMTSL3 | FRK | ENSP00000286744 | ENSP00000476145 | ADAMTS-like protein 3; ADAMTS like 3. | Tyrosine-protein kinase FRK; Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor. | 0.792 |
| ADAMTSL3 | KIAA1328 | ENSP00000286744 | ENSP00000280020 | ADAMTS-like protein 3; ADAMTS like 3. | Protein hinderin; Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes. | 0.999 |
| ADAMTSL3 | WDPCP | ENSP00000286744 | ENSP00000272321 | ADAMTS-like protein 3; ADAMTS like 3. | WD repeat-containing and planar cell polarity effector protein fritz homolog; Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements. Together with FUZ and WDPCP proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (By similarity). | 0.776 |
| ASTN2 | ADAMTSL3 | ENSP00000354504 | ENSP00000286744 | Astrotactin-2; Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (By similarity). Selectively binds inositol-4,5- bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5- tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup. | ADAMTS-like protein 3; ADAMTS like 3. | 0.998 |
| ASTN2 | FAM228B | ENSP00000354504 | ENSP00000482482 | Astrotactin-2; Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (By similarity). Selectively binds inositol-4,5- bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5- tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup. | Protein FAM228B; Family with sequence similarity 228 member B; Belongs to the FAM228 family. | 0.764 |
| ASTN2 | FRK | ENSP00000354504 | ENSP00000476145 | Astrotactin-2; Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (By similarity). Selectively binds inositol-4,5- bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5- tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup. | Tyrosine-protein kinase FRK; Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor. | 0.999 |
| ASTN2 | INTU | ENSP00000354504 | ENSP00000334003 | Astrotactin-2; Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (By similarity). Selectively binds inositol-4,5- bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5- tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup. | Protein inturned; Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity ef [...] | 0.663 |
| ASTN2 | KIAA1328 | ENSP00000354504 | ENSP00000280020 | Astrotactin-2; Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (By similarity). Selectively binds inositol-4,5- bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5- tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup. | Protein hinderin; Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes. | 0.999 |
| ASTN2 | WDPCP | ENSP00000354504 | ENSP00000272321 | Astrotactin-2; Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (By similarity). Selectively binds inositol-4,5- bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5- tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup. | WD repeat-containing and planar cell polarity effector protein fritz homolog; Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements. Together with FUZ and WDPCP proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (By similarity). | 0.819 |
| BET1L | FAM228B | ENSP00000372210 | ENSP00000482482 | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity). | Protein FAM228B; Family with sequence similarity 228 member B; Belongs to the FAM228 family. | 0.591 |
| CCDC144A | FAM228B | ENSP00000353717 | ENSP00000482482 | Coiled-coil domain containing 144A. | Protein FAM228B; Family with sequence similarity 228 member B; Belongs to the FAM228 family. | 0.472 |
| FAM228B | ADAMTSL3 | ENSP00000482482 | ENSP00000286744 | Protein FAM228B; Family with sequence similarity 228 member B; Belongs to the FAM228 family. | ADAMTS-like protein 3; ADAMTS like 3. | 0.493 |
| FAM228B | ASTN2 | ENSP00000482482 | ENSP00000354504 | Protein FAM228B; Family with sequence similarity 228 member B; Belongs to the FAM228 family. | Astrotactin-2; Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (By similarity). Selectively binds inositol-4,5- bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5- tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup. | 0.764 |
| FAM228B | BET1L | ENSP00000482482 | ENSP00000372210 | Protein FAM228B; Family with sequence similarity 228 member B; Belongs to the FAM228 family. | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity). | 0.591 |
| FAM228B | CCDC144A | ENSP00000482482 | ENSP00000353717 | Protein FAM228B; Family with sequence similarity 228 member B; Belongs to the FAM228 family. | Coiled-coil domain containing 144A. | 0.472 |
| FAM228B | FRK | ENSP00000482482 | ENSP00000476145 | Protein FAM228B; Family with sequence similarity 228 member B; Belongs to the FAM228 family. | Tyrosine-protein kinase FRK; Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor. | 0.483 |
| FAM228B | INTU | ENSP00000482482 | ENSP00000334003 | Protein FAM228B; Family with sequence similarity 228 member B; Belongs to the FAM228 family. | Protein inturned; Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity ef [...] | 0.483 |
| FAM228B | KIAA1328 | ENSP00000482482 | ENSP00000280020 | Protein FAM228B; Family with sequence similarity 228 member B; Belongs to the FAM228 family. | Protein hinderin; Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes. | 0.517 |
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