FAM228B protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CFAP20	CFAP54	ENSP00000262498	ENSP00000431759	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Cilia- and flagella-associated protein 54; Required for assembly and function of cilia and flagella.	0.793
CFAP20	CFAP69	ENSP00000262498	ENSP00000373948	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Cilia- and flagella-associated protein 69; Cilium- and flagellum-associated protein. In the olfactory epithelium, regulates the speed of activation and termination of the odor response and thus contributes to the robustness of olfactory transduction pathways (By similarity). Required for sperm flagellum assembly and stability.	0.641
CFAP20	CFAP70	ENSP00000262498	ENSP00000310829	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Cilia and flagella associated protein 70; Belongs to the CFAP70 family.	0.677
CFAP20	DLEC1	ENSP00000262498	ENSP00000308597	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Deleted in lung and esophageal cancer protein 1; May act as a tumor suppressor by inhibiting cell proliferation.	0.642
CFAP20	FAM228B	ENSP00000262498	ENSP00000482482	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Protein FAM228B; Family with sequence similarity 228 member B; Belongs to the FAM228 family.	0.641
CFAP20	GOT1L1	ENSP00000262498	ENSP00000303077	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Putative aspartate aminotransferase, cytoplasmic 2; Glutamic-oxaloacetic transaminase 1 like 1.	0.641
CFAP20	LRGUK	ENSP00000262498	ENSP00000285928	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Leucine-rich repeat and guanylate kinase domain-containing protein; Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis.	0.641
CFAP20	MAP1S	ENSP00000262498	ENSP00000325313	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Microtubule-associated protein 1S; Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity); Belongs to the MAP1 family.	0.641
CFAP20	SPATA17	ENSP00000262498	ENSP00000355900	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Spermatogenesis-associated protein 17; Spermatogenesis associated 17.	0.641
CFAP20	SPATA4	ENSP00000262498	ENSP00000280191	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	Spermatogenesis-associated protein 4; May play a role in apoptosis regulation.	0.641
CFAP54	CFAP20	ENSP00000431759	ENSP00000262498	Cilia- and flagella-associated protein 54; Required for assembly and function of cilia and flagella.	Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation.	0.793
CFAP54	CFAP69	ENSP00000431759	ENSP00000373948	Cilia- and flagella-associated protein 54; Required for assembly and function of cilia and flagella.	Cilia- and flagella-associated protein 69; Cilium- and flagellum-associated protein. In the olfactory epithelium, regulates the speed of activation and termination of the odor response and thus contributes to the robustness of olfactory transduction pathways (By similarity). Required for sperm flagellum assembly and stability.	0.773
CFAP54	CFAP70	ENSP00000431759	ENSP00000310829	Cilia- and flagella-associated protein 54; Required for assembly and function of cilia and flagella.	Cilia and flagella associated protein 70; Belongs to the CFAP70 family.	0.718
CFAP54	DLEC1	ENSP00000431759	ENSP00000308597	Cilia- and flagella-associated protein 54; Required for assembly and function of cilia and flagella.	Deleted in lung and esophageal cancer protein 1; May act as a tumor suppressor by inhibiting cell proliferation.	0.707
CFAP54	FAM228B	ENSP00000431759	ENSP00000482482	Cilia- and flagella-associated protein 54; Required for assembly and function of cilia and flagella.	Protein FAM228B; Family with sequence similarity 228 member B; Belongs to the FAM228 family.	0.696
CFAP54	GOT1L1	ENSP00000431759	ENSP00000303077	Cilia- and flagella-associated protein 54; Required for assembly and function of cilia and flagella.	Putative aspartate aminotransferase, cytoplasmic 2; Glutamic-oxaloacetic transaminase 1 like 1.	0.641
CFAP54	LRGUK	ENSP00000431759	ENSP00000285928	Cilia- and flagella-associated protein 54; Required for assembly and function of cilia and flagella.	Leucine-rich repeat and guanylate kinase domain-containing protein; Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis.	0.755
CFAP54	MAP1S	ENSP00000431759	ENSP00000325313	Cilia- and flagella-associated protein 54; Required for assembly and function of cilia and flagella.	Microtubule-associated protein 1S; Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity); Belongs to the MAP1 family.	0.641
CFAP54	SPATA17	ENSP00000431759	ENSP00000355900	Cilia- and flagella-associated protein 54; Required for assembly and function of cilia and flagella.	Spermatogenesis-associated protein 17; Spermatogenesis associated 17.	0.641
CFAP54	SPATA4	ENSP00000431759	ENSP00000280191	Cilia- and flagella-associated protein 54; Required for assembly and function of cilia and flagella.	Spermatogenesis-associated protein 4; May play a role in apoptosis regulation.	0.641