node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AK7 | RSPH9 | ENSP00000267584 | ENSP00000361238 | Adenylate kinase 7; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. Involved in maintaining ciliary structure and function. | Radial spoke head protein 9 homolog; Probable component of the axonemal radial spoke head. Radial spokes are regularly spaced along cilia, sperm and flagella axonemes. They consist of a thin stalk, which is attached to a subfiber of the outer doublet microtubule, and a bulbous head, which is attached to the stalk and appears to interact with the projections from the central pair of microtubules. | 0.753 |
AK7 | WDR38 | ENSP00000267584 | ENSP00000483312 | Adenylate kinase 7; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. Involved in maintaining ciliary structure and function. | WD repeat domain 38. | 0.655 |
ANKEF1 | RSPH14 | ENSP00000367644 | ENSP00000216036 | Ankyrin repeat and EF-hand domain containing 1. | Radial spoke head 14 homolog; Belongs to the flagellar radial spoke RSP14 family. | 0.634 |
ANKEF1 | WDR38 | ENSP00000367644 | ENSP00000483312 | Ankyrin repeat and EF-hand domain containing 1. | WD repeat domain 38. | 0.619 |
ASH2L | RBBP5 | ENSP00000340896 | ENSP00000264515 | Set1/Ash2 histone methyltransferase complex subunit ASH2; Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis. In association with RBBP5 and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B. | Retinoblastoma-binding protein 5; In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid (By similarity). As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. In association with ASH2L and WDR5, stimulates the histone methyltransferase activities of KMT2 [...] | 0.999 |
ASH2L | WDR38 | ENSP00000340896 | ENSP00000483312 | Set1/Ash2 histone methyltransferase complex subunit ASH2; Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis. In association with RBBP5 and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B. | WD repeat domain 38. | 0.594 |
ERICH2 | FAM81B | ENSP00000387298 | ENSP00000283357 | Glutamate-rich protein 2; Glutamate rich 2. | Protein FAM81B; Family with sequence similarity 81 member B. | 0.594 |
ERICH2 | WDR38 | ENSP00000387298 | ENSP00000483312 | Glutamate-rich protein 2; Glutamate rich 2. | WD repeat domain 38. | 0.594 |
FAM81B | ERICH2 | ENSP00000283357 | ENSP00000387298 | Protein FAM81B; Family with sequence similarity 81 member B. | Glutamate-rich protein 2; Glutamate rich 2. | 0.594 |
FAM81B | RSPH14 | ENSP00000283357 | ENSP00000216036 | Protein FAM81B; Family with sequence similarity 81 member B. | Radial spoke head 14 homolog; Belongs to the flagellar radial spoke RSP14 family. | 0.605 |
FAM81B | WDR38 | ENSP00000283357 | ENSP00000483312 | Protein FAM81B; Family with sequence similarity 81 member B. | WD repeat domain 38. | 0.620 |
FLACC1 | RSPH9 | ENSP00000385098 | ENSP00000361238 | Flagellum-associated coiled-coil domain-containing protein 1; Flagellum associated containing coiled-coil domains 1. | Radial spoke head protein 9 homolog; Probable component of the axonemal radial spoke head. Radial spokes are regularly spaced along cilia, sperm and flagella axonemes. They consist of a thin stalk, which is attached to a subfiber of the outer doublet microtubule, and a bulbous head, which is attached to the stalk and appears to interact with the projections from the central pair of microtubules. | 0.604 |
FLACC1 | WDR38 | ENSP00000385098 | ENSP00000483312 | Flagellum-associated coiled-coil domain-containing protein 1; Flagellum associated containing coiled-coil domains 1. | WD repeat domain 38. | 0.633 |
OR1Q1 | WDR38 | ENSP00000297913 | ENSP00000483312 | Olfactory receptor 1Q1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | WD repeat domain 38. | 0.588 |
RBBP5 | ASH2L | ENSP00000264515 | ENSP00000340896 | Retinoblastoma-binding protein 5; In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid (By similarity). As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. In association with ASH2L and WDR5, stimulates the histone methyltransferase activities of KMT2 [...] | Set1/Ash2 histone methyltransferase complex subunit ASH2; Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis. In association with RBBP5 and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B. | 0.999 |
RBBP5 | WDR38 | ENSP00000264515 | ENSP00000483312 | Retinoblastoma-binding protein 5; In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid (By similarity). As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. In association with ASH2L and WDR5, stimulates the histone methyltransferase activities of KMT2 [...] | WD repeat domain 38. | 0.596 |
RSPH14 | ANKEF1 | ENSP00000216036 | ENSP00000367644 | Radial spoke head 14 homolog; Belongs to the flagellar radial spoke RSP14 family. | Ankyrin repeat and EF-hand domain containing 1. | 0.634 |
RSPH14 | FAM81B | ENSP00000216036 | ENSP00000283357 | Radial spoke head 14 homolog; Belongs to the flagellar radial spoke RSP14 family. | Protein FAM81B; Family with sequence similarity 81 member B. | 0.605 |
RSPH14 | RSPH9 | ENSP00000216036 | ENSP00000361238 | Radial spoke head 14 homolog; Belongs to the flagellar radial spoke RSP14 family. | Radial spoke head protein 9 homolog; Probable component of the axonemal radial spoke head. Radial spokes are regularly spaced along cilia, sperm and flagella axonemes. They consist of a thin stalk, which is attached to a subfiber of the outer doublet microtubule, and a bulbous head, which is attached to the stalk and appears to interact with the projections from the central pair of microtubules. | 0.448 |
RSPH14 | WDR38 | ENSP00000216036 | ENSP00000483312 | Radial spoke head 14 homolog; Belongs to the flagellar radial spoke RSP14 family. | WD repeat domain 38. | 0.686 |