| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CDC123 | ZSCAN26 | ENSP00000281141 | ENSP00000485228 | Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. | Zinc finger and SCAN domain-containing protein 26; May be involved in transcriptional regulation. | 0.457 |
| KRTAP10-7 | ZSCAN26 | ENSP00000476821 | ENSP00000485228 | Keratin-associated protein 10-7; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 10 family. | Zinc finger and SCAN domain-containing protein 26; May be involved in transcriptional regulation. | 0.855 |
| LRP4 | ZSCAN26 | ENSP00000367888 | ENSP00000485228 | Low-density lipoprotein receptor-related protein 4; Mediates SOST-dependent inhibition of bone formation. Functions as a specific facilitator of SOST-mediated inhibition of Wnt signaling. Plays a key role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between motor neuron and skeletal muscle. Directly binds AGRIN and recruits it to the MUSK signaling complex. Mediates the AGRIN-induced phosphorylation of MUSK, the kinase of the complex. The activation of MUSK in myotubes induces the formation of NMJ by regulating different processes including the [...] | Zinc finger and SCAN domain-containing protein 26; May be involved in transcriptional regulation. | 0.654 |
| NKAPL | ZKSCAN4 | ENSP00000345716 | ENSP00000366509 | NKAP-like protein; Transcriptional repressor of Notch-mediated signaling. Required for spermatogenesis. | Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.711 |
| NKAPL | ZSCAN26 | ENSP00000345716 | ENSP00000485228 | NKAP-like protein; Transcriptional repressor of Notch-mediated signaling. Required for spermatogenesis. | Zinc finger and SCAN domain-containing protein 26; May be involved in transcriptional regulation. | 0.507 |
| RNF112 | RPL26L1 | ENSP00000454919 | ENSP00000428223 | RING finger protein 112; E3 ubiquitin-protein ligase that plays an important role in neuronal differentiation, including neurogenesis and gliogenesis, during brain development. During embryonic development initiates neuronal differentiation by inducing cell cycle arrest at the G0/G1 phase through up-regulation of cell-cycle regulatory proteins. Plays a role not only in the fetal period during the development of the nervous system, but also in the adult brain, where it is involved in the maintenance of neural functions and protection of the nervous tissue cells from oxidative stress-ind [...] | Ribosomal protein L26 like 1; Belongs to the universal ribosomal protein uL24 family. | 0.457 |
| RNF112 | ZKSCAN4 | ENSP00000454919 | ENSP00000366509 | RING finger protein 112; E3 ubiquitin-protein ligase that plays an important role in neuronal differentiation, including neurogenesis and gliogenesis, during brain development. During embryonic development initiates neuronal differentiation by inducing cell cycle arrest at the G0/G1 phase through up-regulation of cell-cycle regulatory proteins. Plays a role not only in the fetal period during the development of the nervous system, but also in the adult brain, where it is involved in the maintenance of neural functions and protection of the nervous tissue cells from oxidative stress-ind [...] | Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.457 |
| RNF112 | ZSCAN26 | ENSP00000454919 | ENSP00000485228 | RING finger protein 112; E3 ubiquitin-protein ligase that plays an important role in neuronal differentiation, including neurogenesis and gliogenesis, during brain development. During embryonic development initiates neuronal differentiation by inducing cell cycle arrest at the G0/G1 phase through up-regulation of cell-cycle regulatory proteins. Plays a role not only in the fetal period during the development of the nervous system, but also in the adult brain, where it is involved in the maintenance of neural functions and protection of the nervous tissue cells from oxidative stress-ind [...] | Zinc finger and SCAN domain-containing protein 26; May be involved in transcriptional regulation. | 0.457 |
| RNF4 | ZSCAN26 | ENSP00000426503 | ENSP00000485228 | E3 ubiquitin-protein ligase RNF4; E3 ubiquitin-protein ligase which binds polysumoylated chains covalently attached to proteins and mediates 'Lys-6'-, 'Lys-11'-, 'Lys- 48'- and 'Lys-63'-linked polyubiquitination of those substrates and their subsequent targeting to the proteasome for degradation. Regulates the degradation of several proteins including PML and the transcriptional activator PEA3. Involved in chromosome alignment and spindle assembly, it regulates the kinetochore CENPH-CENPI-CENPK complex by targeting polysumoylated CENPI to proteasomal degradation. Regulates the cellular [...] | Zinc finger and SCAN domain-containing protein 26; May be involved in transcriptional regulation. | 0.457 |
| RPL26L1 | RNF112 | ENSP00000428223 | ENSP00000454919 | Ribosomal protein L26 like 1; Belongs to the universal ribosomal protein uL24 family. | RING finger protein 112; E3 ubiquitin-protein ligase that plays an important role in neuronal differentiation, including neurogenesis and gliogenesis, during brain development. During embryonic development initiates neuronal differentiation by inducing cell cycle arrest at the G0/G1 phase through up-regulation of cell-cycle regulatory proteins. Plays a role not only in the fetal period during the development of the nervous system, but also in the adult brain, where it is involved in the maintenance of neural functions and protection of the nervous tissue cells from oxidative stress-ind [...] | 0.457 |
| RPL26L1 | SART3 | ENSP00000428223 | ENSP00000449386 | Ribosomal protein L26 like 1; Belongs to the universal ribosomal protein uL24 family. | Squamous cell carcinoma antigen recognized by T-cells 3; U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation. Also binds U6atac snRNPs and may function as a recycling factor for U4atac/U6atac spliceosomal snRNP, an initial step in the assembly of U12-type spliceosomal complex. The U12-type spliceosomal complex plays a role in the splicing of introns with non- canonical splice sites. May also function as a substrate-targeting factor [...] | 0.912 |
| RPL26L1 | ZSCAN26 | ENSP00000428223 | ENSP00000485228 | Ribosomal protein L26 like 1; Belongs to the universal ribosomal protein uL24 family. | Zinc finger and SCAN domain-containing protein 26; May be involved in transcriptional regulation. | 0.543 |
| SART3 | RPL26L1 | ENSP00000449386 | ENSP00000428223 | Squamous cell carcinoma antigen recognized by T-cells 3; U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation. Also binds U6atac snRNPs and may function as a recycling factor for U4atac/U6atac spliceosomal snRNP, an initial step in the assembly of U12-type spliceosomal complex. The U12-type spliceosomal complex plays a role in the splicing of introns with non- canonical splice sites. May also function as a substrate-targeting factor [...] | Ribosomal protein L26 like 1; Belongs to the universal ribosomal protein uL24 family. | 0.912 |
| SART3 | ZSCAN26 | ENSP00000449386 | ENSP00000485228 | Squamous cell carcinoma antigen recognized by T-cells 3; U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation. Also binds U6atac snRNPs and may function as a recycling factor for U4atac/U6atac spliceosomal snRNP, an initial step in the assembly of U12-type spliceosomal complex. The U12-type spliceosomal complex plays a role in the splicing of introns with non- canonical splice sites. May also function as a substrate-targeting factor [...] | Zinc finger and SCAN domain-containing protein 26; May be involved in transcriptional regulation. | 0.610 |
| TRIM11 | ZSCAN26 | ENSP00000284551 | ENSP00000485228 | E3 ubiquitin-protein ligase TRIM11; E3 ubiquitin-protein ligase that promotes the degradation of insoluble ubiquitinated proteins, including insoluble PAX6, poly-Gln repeat expanded HTT and poly-Ala repeat expanded ARX. Mediates PAX6 ubiquitination leading to proteasomal degradation, thereby modulating cortical neurogenesis. May also inhibit PAX6 transcriptional activity, possibly in part by preventing the binding of PAX6 to its consensus sequences. May contribute to the regulation of the intracellular level of HN (humanin) or HN-containing proteins through the proteasomal degradation [...] | Zinc finger and SCAN domain-containing protein 26; May be involved in transcriptional regulation. | 0.624 |
| ZKSCAN4 | NKAPL | ENSP00000366509 | ENSP00000345716 | Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family. | NKAP-like protein; Transcriptional repressor of Notch-mediated signaling. Required for spermatogenesis. | 0.711 |
| ZKSCAN4 | RNF112 | ENSP00000366509 | ENSP00000454919 | Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family. | RING finger protein 112; E3 ubiquitin-protein ligase that plays an important role in neuronal differentiation, including neurogenesis and gliogenesis, during brain development. During embryonic development initiates neuronal differentiation by inducing cell cycle arrest at the G0/G1 phase through up-regulation of cell-cycle regulatory proteins. Plays a role not only in the fetal period during the development of the nervous system, but also in the adult brain, where it is involved in the maintenance of neural functions and protection of the nervous tissue cells from oxidative stress-ind [...] | 0.457 |
| ZKSCAN4 | ZSCAN26 | ENSP00000366509 | ENSP00000485228 | Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger and SCAN domain-containing protein 26; May be involved in transcriptional regulation. | 0.550 |
| ZSCAN26 | CDC123 | ENSP00000485228 | ENSP00000281141 | Zinc finger and SCAN domain-containing protein 26; May be involved in transcriptional regulation. | Cell division cycle protein 123 homolog; Required for S phase entry of the cell cycle. | 0.457 |
| ZSCAN26 | KRTAP10-7 | ENSP00000485228 | ENSP00000476821 | Zinc finger and SCAN domain-containing protein 26; May be involved in transcriptional regulation. | Keratin-associated protein 10-7; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 10 family. | 0.855 |
