STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HMCN2Hemicentin-2; Hemicentin 2. (5059 aa)    
Predicted Functional Partners:
SLC36A3
Proton-coupled amino acid transporter 3; Solute carrier family 36 member 3.
      
 0.556
HDGFL3
Hepatoma-derived growth factor-related protein 3; Enhances DNA synthesis and may play a role in cell proliferation.
    
 
 0.507
NTM
Neurotrimin; Neural cell adhesion molecule; Belongs to the immunoglobulin superfamily. IgLON family.
    
 
0.450
GPX3
Glutathione peroxidase 3; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.
      
 0.408
OR14A16
Olfactory receptor 14A16; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.406
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.