| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CEL | CELA3B | ENSP00000501111 | ENSP00000338369 | Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs (By similarity). Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins. Belongs to the type-B carboxylesterase/ [...] | Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity. | 0.941 |
| CEL | CPA1 | ENSP00000501111 | ENSP00000011292 | Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs (By similarity). Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins. Belongs to the type-B carboxylesterase/ [...] | Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro; Belongs to the peptidase M14 family. | 0.983 |
| CEL | CTRB1 | ENSP00000501111 | ENSP00000354294 | Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs (By similarity). Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins. Belongs to the type-B carboxylesterase/ [...] | Chymotrypsinogen B1; Belongs to the peptidase S1 family. | 0.958 |
| CEL | CTRB2 | ENSP00000501111 | ENSP00000303963 | Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs (By similarity). Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins. Belongs to the type-B carboxylesterase/ [...] | Chymotrypsinogen B2; Belongs to the peptidase S1 family. | 0.951 |
| CEL | CTRL | ENSP00000501111 | ENSP00000458537 | Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs (By similarity). Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins. Belongs to the type-B carboxylesterase/ [...] | Chymotrypsin-like protease CTRL-1; Chymotrypsin like; Belongs to the peptidase S1 family. | 0.982 |
| CEL | LIPF | ENSP00000501111 | ENSP00000377900 | Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs (By similarity). Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins. Belongs to the type-B carboxylesterase/ [...] | Lipase F, gastric type. | 0.948 |
| CEL | LPL | ENSP00000501111 | ENSP00000497642 | Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs (By similarity). Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins. Belongs to the type-B carboxylesterase/ [...] | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. | 0.939 |
| CEL | PNLIP | ENSP00000501111 | ENSP00000358223 | Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs (By similarity). Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins. Belongs to the type-B carboxylesterase/ [...] | Pancreatic lipase; Belongs to the AB hydrolase superfamily. Lipase family. | 0.981 |
| CEL | PNLIPRP1 | ENSP00000501111 | ENSP00000433933 | Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs (By similarity). Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins. Belongs to the type-B carboxylesterase/ [...] | Inactive pancreatic lipase-related protein 1; May function as inhibitor of dietary triglyceride digestion. Lacks detectable lipase activity towards triglycerides, diglycerides, phosphatidylcholine, galactolipids or cholesterol esters (in vitro) (By similarity); Belongs to the AB hydrolase superfamily. Lipase family. | 0.967 |
| CEL | PNLIPRP3 | ENSP00000501111 | ENSP00000358232 | Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs (By similarity). Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins. Belongs to the type-B carboxylesterase/ [...] | Pancreatic lipase related protein 3. | 0.945 |
| CELA3B | CEL | ENSP00000338369 | ENSP00000501111 | Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity. | Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs (By similarity). Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins. Belongs to the type-B carboxylesterase/ [...] | 0.941 |
| CELA3B | CPA1 | ENSP00000338369 | ENSP00000011292 | Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity. | Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro; Belongs to the peptidase M14 family. | 0.997 |
| CELA3B | CTRB1 | ENSP00000338369 | ENSP00000354294 | Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity. | Chymotrypsinogen B1; Belongs to the peptidase S1 family. | 0.921 |
| CELA3B | CTRB2 | ENSP00000338369 | ENSP00000303963 | Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity. | Chymotrypsinogen B2; Belongs to the peptidase S1 family. | 0.927 |
| CELA3B | CTRL | ENSP00000338369 | ENSP00000458537 | Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity. | Chymotrypsin-like protease CTRL-1; Chymotrypsin like; Belongs to the peptidase S1 family. | 0.924 |
| CELA3B | PNLIP | ENSP00000338369 | ENSP00000358223 | Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity. | Pancreatic lipase; Belongs to the AB hydrolase superfamily. Lipase family. | 0.844 |
| CELA3B | PNLIPRP1 | ENSP00000338369 | ENSP00000433933 | Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity. | Inactive pancreatic lipase-related protein 1; May function as inhibitor of dietary triglyceride digestion. Lacks detectable lipase activity towards triglycerides, diglycerides, phosphatidylcholine, galactolipids or cholesterol esters (in vitro) (By similarity); Belongs to the AB hydrolase superfamily. Lipase family. | 0.665 |
| CPA1 | CEL | ENSP00000011292 | ENSP00000501111 | Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro; Belongs to the peptidase M14 family. | Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs (By similarity). Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins. Belongs to the type-B carboxylesterase/ [...] | 0.983 |
| CPA1 | CELA3B | ENSP00000011292 | ENSP00000338369 | Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro; Belongs to the peptidase M14 family. | Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity. | 0.997 |
| CPA1 | CTRB1 | ENSP00000011292 | ENSP00000354294 | Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro; Belongs to the peptidase M14 family. | Chymotrypsinogen B1; Belongs to the peptidase S1 family. | 0.988 |
