H4C11 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

H4C11

H4 clustered histone 11. (103 aa)

Predicted Functional Partners:

H4C12

0.997

H2BC7

0.971

H2BC6

0.971

H2BC10

0.970

H3C7

0.970

H3C4

0.969

H3C8

0.969

H3C10

0.967

H2AC6

0.967

H3C1

0.967

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H2AC6	H2BC10	ENSP00000367022	ENSP00000366962	Histone H2A type 1-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H2B clustered histone 10.	0.991
H2AC6	H2BC6	ENSP00000367022	ENSP00000489317	Histone H2A type 1-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H2B clustered histone 6.	0.996
H2AC6	H2BC7	ENSP00000367022	ENSP00000348924	Histone H2A type 1-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H2B clustered histone 7.	0.995
H2AC6	H3C1	ENSP00000367022	ENSP00000480826	Histone H2A type 1-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H3 clustered histone 1.	0.978
H2AC6	H3C10	ENSP00000367022	ENSP00000358160	Histone H2A type 1-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H3 clustered histone 10.	0.990
H2AC6	H3C4	ENSP00000367022	ENSP00000366999	Histone H2A type 1-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H3 clustered histone 4.	0.959
H2AC6	H3C7	ENSP00000367022	ENSP00000484095	Histone H2A type 1-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H3 clustered histone 7.	0.969
H2AC6	H3C8	ENSP00000367022	ENSP00000484638	Histone H2A type 1-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H3 clustered histone 8.	0.965
H2AC6	H4C11	ENSP00000367022	ENSP00000347168	Histone H2A type 1-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H4 clustered histone 11.	0.967
H2AC6	H4C12	ENSP00000367022	ENSP00000479794	Histone H2A type 1-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	H4 clustered histone 12.	0.966
H2BC10	H2AC6	ENSP00000366962	ENSP00000367022	H2B clustered histone 10.	Histone H2A type 1-C; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.991
H2BC10	H2BC6	ENSP00000366962	ENSP00000489317	H2B clustered histone 10.	H2B clustered histone 6.	0.972
H2BC10	H2BC7	ENSP00000366962	ENSP00000348924	H2B clustered histone 10.	H2B clustered histone 7.	0.984
H2BC10	H3C1	ENSP00000366962	ENSP00000480826	H2B clustered histone 10.	H3 clustered histone 1.	0.926
H2BC10	H3C10	ENSP00000366962	ENSP00000358160	H2B clustered histone 10.	H3 clustered histone 10.	0.934
H2BC10	H3C4	ENSP00000366962	ENSP00000366999	H2B clustered histone 10.	H3 clustered histone 4.	0.951
H2BC10	H3C7	ENSP00000366962	ENSP00000484095	H2B clustered histone 10.	H3 clustered histone 7.	0.936
H2BC10	H3C8	ENSP00000366962	ENSP00000484638	H2B clustered histone 10.	H3 clustered histone 8.	0.947
H2BC10	H4C11	ENSP00000366962	ENSP00000347168	H2B clustered histone 10.	H4 clustered histone 11.	0.970
H2BC10	H4C12	ENSP00000366962	ENSP00000479794	H2B clustered histone 10.	H4 clustered histone 12.	0.965