ANKRD40CL protein (human) - STRING interaction network

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ANKRD40CL

Putative ANKRD40 C-terminal-like protein; ANKRD40 C-terminal like. (114 aa)

Predicted Functional Partners:

SEC24A

0.549

SEC24B

0.549

SEC16B

0.493

SEC16A

0.493

ANKRD34B

0.469

ANKRD66

0.450

DDX17

0.442

SAR1A

0.404

SAR1B

0.404

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD34B	ANKRD40CL	ENSP00000339802	ENSP00000494384	Ankyrin repeat domain 34B; Belongs to the ANKRD34 family.	Putative ANKRD40 C-terminal-like protein; ANKRD40 C-terminal like.	0.469
ANKRD40CL	ANKRD34B	ENSP00000494384	ENSP00000339802	Putative ANKRD40 C-terminal-like protein; ANKRD40 C-terminal like.	Ankyrin repeat domain 34B; Belongs to the ANKRD34 family.	0.469
ANKRD40CL	ANKRD66	ENSP00000494384	ENSP00000454770	Putative ANKRD40 C-terminal-like protein; ANKRD40 C-terminal like.	Ankyrin repeat domain 66.	0.450
ANKRD40CL	DDX17	ENSP00000494384	ENSP00000380033	Putative ANKRD40 C-terminal-like protein; ANKRD40 C-terminal like.	Probable ATP-dependent RNA helicase DDX17; As an RNA helicase, unwinds RNA and alters RNA structures through ATP binding and hydrolysis. Involved in multiple cellular processes, including pre-mRNA splicing, alternative splicing, ribosomal RNA processing and miRNA processing, as well as transcription regulation. Regulates the alternative splicing of exons exhibiting specific features. For instance, promotes the inclusion of AC-rich alternative exons in CD44 transcripts. This function requires the RNA helicase activity. Affects NFAT5 and histone macro- H2A.1/MACROH2A1 alternative splicin [...]	0.442
ANKRD40CL	SAR1A	ENSP00000494384	ENSP00000362339	Putative ANKRD40 C-terminal-like protein; ANKRD40 C-terminal like.	GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).	0.404
ANKRD40CL	SAR1B	ENSP00000494384	ENSP00000385432	Putative ANKRD40 C-terminal-like protein; ANKRD40 C-terminal like.	GTP-binding protein SAR1b; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex.	0.404
ANKRD40CL	SEC16A	ENSP00000494384	ENSP00000325827	Putative ANKRD40 C-terminal-like protein; ANKRD40 C-terminal like.	Protein transport protein Sec16A; Acts as a molecular scaffold that plays a key role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining an ERES. Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. Mediates the recruitment of MIA3/TANGO to ERES. Regulates both conventional (ER/Golgi-dependent) and GORASP2-mediated unconventional (ER/Golgi-independent) trafficking of CFTR to cell mem [...]	0.493
ANKRD40CL	SEC16B	ENSP00000494384	ENSP00000308339	Putative ANKRD40 C-terminal-like protein; ANKRD40 C-terminal like.	Protein transport protein Sec16B; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes ; Belongs to the SEC16 family.	0.493
ANKRD40CL	SEC24A	ENSP00000494384	ENSP00000381823	Putative ANKRD40 C-terminal-like protein; ANKRD40 C-terminal like.	Protein transport protein Sec24A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24B may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may [...]	0.549
ANKRD40CL	SEC24B	ENSP00000494384	ENSP00000428564	Putative ANKRD40 C-terminal-like protein; ANKRD40 C-terminal like.	Protein transport protein Sec24B; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24A may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may [...]	0.549
ANKRD66	ANKRD40CL	ENSP00000454770	ENSP00000494384	Ankyrin repeat domain 66.	Putative ANKRD40 C-terminal-like protein; ANKRD40 C-terminal like.	0.450
DDX17	ANKRD40CL	ENSP00000380033	ENSP00000494384	Probable ATP-dependent RNA helicase DDX17; As an RNA helicase, unwinds RNA and alters RNA structures through ATP binding and hydrolysis. Involved in multiple cellular processes, including pre-mRNA splicing, alternative splicing, ribosomal RNA processing and miRNA processing, as well as transcription regulation. Regulates the alternative splicing of exons exhibiting specific features. For instance, promotes the inclusion of AC-rich alternative exons in CD44 transcripts. This function requires the RNA helicase activity. Affects NFAT5 and histone macro- H2A.1/MACROH2A1 alternative splicin [...]	Putative ANKRD40 C-terminal-like protein; ANKRD40 C-terminal like.	0.442
SAR1A	ANKRD40CL	ENSP00000362339	ENSP00000494384	GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).	Putative ANKRD40 C-terminal-like protein; ANKRD40 C-terminal like.	0.404
SAR1A	SAR1B	ENSP00000362339	ENSP00000385432	GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).	GTP-binding protein SAR1b; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex.	0.999
SAR1A	SEC16A	ENSP00000362339	ENSP00000325827	GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).	Protein transport protein Sec16A; Acts as a molecular scaffold that plays a key role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining an ERES. Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. Mediates the recruitment of MIA3/TANGO to ERES. Regulates both conventional (ER/Golgi-dependent) and GORASP2-mediated unconventional (ER/Golgi-independent) trafficking of CFTR to cell mem [...]	0.991
SAR1A	SEC16B	ENSP00000362339	ENSP00000308339	GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).	Protein transport protein Sec16B; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes ; Belongs to the SEC16 family.	0.886
SAR1A	SEC24A	ENSP00000362339	ENSP00000381823	GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).	Protein transport protein Sec24A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24B may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may [...]	0.999
SAR1A	SEC24B	ENSP00000362339	ENSP00000428564	GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).	Protein transport protein Sec24B; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24A may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may [...]	0.999
SAR1B	ANKRD40CL	ENSP00000385432	ENSP00000494384	GTP-binding protein SAR1b; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex.	Putative ANKRD40 C-terminal-like protein; ANKRD40 C-terminal like.	0.404
SAR1B	SAR1A	ENSP00000385432	ENSP00000362339	GTP-binding protein SAR1b; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex.	GTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).	0.999