| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACBD3 | ARMH3 | ENSP00000355777 | ENSP00000359050 | Golgi resident protein GCP60, N-terminally processed; Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi. Involved in hormone-induced steroid biosynthesis in testicular Leydig cells (By similarity). Recruits PI4KB to the Golgi apparatus membrane; enhances the enzyme activity of PI4KB activity via its membrane recruitment thereby increasing the local concentration of the substrate in the vicinity of the kinase. | Armadillo-like helical domain-containing protein 3; Involved in GBF1 recruitment, Golgi maintenance and protein secretion. | 0.572 |
| ACBD3 | GBF1 | ENSP00000355777 | ENSP00000359000 | Golgi resident protein GCP60, N-terminally processed; Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi. Involved in hormone-induced steroid biosynthesis in testicular Leydig cells (By similarity). Recruits PI4KB to the Golgi apparatus membrane; enhances the enzyme activity of PI4KB activity via its membrane recruitment thereby increasing the local concentration of the substrate in the vicinity of the kinase. | Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1; Guanine-nucleotide exchange factor (GEF) for members of the Arf family of small GTPases involved in trafficking in the early secretory pathway; its GEF activity initiates the coating of nascent vesicles via the localized generation of activated ARFs through replacement of GDP with GTP. Recruitment to cis-Golgi membranes requires membrane association of Arf-GDP and can be regulated by ARF1, ARF3, ARF4 and ARF5. Involved in the recruitment of the COPI coat complex to the endoplasmic reticulum exit sites (ERES), a [...] | 0.645 |
| ACBD3 | PI4KB | ENSP00000355777 | ENSP00000357869 | Golgi resident protein GCP60, N-terminally processed; Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi. Involved in hormone-induced steroid biosynthesis in testicular Leydig cells (By similarity). Recruits PI4KB to the Golgi apparatus membrane; enhances the enzyme activity of PI4KB activity via its membrane recruitment thereby increasing the local concentration of the substrate in the vicinity of the kinase. | Phosphatidylinositol 4-kinase beta; Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking (By similarity). | 0.960 |
| ARMH3 | ACBD3 | ENSP00000359050 | ENSP00000355777 | Armadillo-like helical domain-containing protein 3; Involved in GBF1 recruitment, Golgi maintenance and protein secretion. | Golgi resident protein GCP60, N-terminally processed; Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi. Involved in hormone-induced steroid biosynthesis in testicular Leydig cells (By similarity). Recruits PI4KB to the Golgi apparatus membrane; enhances the enzyme activity of PI4KB activity via its membrane recruitment thereby increasing the local concentration of the substrate in the vicinity of the kinase. | 0.572 |
| ARMH3 | CNOT10 | ENSP00000359050 | ENSP00000399862 | Armadillo-like helical domain-containing protein 3; Involved in GBF1 recruitment, Golgi maintenance and protein secretion. | CCR4-NOT transcription complex subunit 10; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex. | 0.561 |
| ARMH3 | COG7 | ENSP00000359050 | ENSP00000305442 | Armadillo-like helical domain-containing protein 3; Involved in GBF1 recruitment, Golgi maintenance and protein secretion. | Conserved oligomeric Golgi complex subunit 7; Required for normal Golgi function. | 0.554 |
| ARMH3 | GBF1 | ENSP00000359050 | ENSP00000359000 | Armadillo-like helical domain-containing protein 3; Involved in GBF1 recruitment, Golgi maintenance and protein secretion. | Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1; Guanine-nucleotide exchange factor (GEF) for members of the Arf family of small GTPases involved in trafficking in the early secretory pathway; its GEF activity initiates the coating of nascent vesicles via the localized generation of activated ARFs through replacement of GDP with GTP. Recruitment to cis-Golgi membranes requires membrane association of Arf-GDP and can be regulated by ARF1, ARF3, ARF4 and ARF5. Involved in the recruitment of the COPI coat complex to the endoplasmic reticulum exit sites (ERES), a [...] | 0.666 |
| ARMH3 | NOL7 | ENSP00000359050 | ENSP00000405674 | Armadillo-like helical domain-containing protein 3; Involved in GBF1 recruitment, Golgi maintenance and protein secretion. | Nucleolar protein 7. | 0.608 |
| ARMH3 | PI4KB | ENSP00000359050 | ENSP00000357869 | Armadillo-like helical domain-containing protein 3; Involved in GBF1 recruitment, Golgi maintenance and protein secretion. | Phosphatidylinositol 4-kinase beta; Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking (By similarity). | 0.924 |
| ARMH3 | SLC4A1AP | ENSP00000359050 | ENSP00000479964 | Armadillo-like helical domain-containing protein 3; Involved in GBF1 recruitment, Golgi maintenance and protein secretion. | Kanadaptin; Solute carrier family 4 member 1 adaptor protein. | 0.512 |
| ARMH3 | TLK2 | ENSP00000359050 | ENSP00000316512 | Armadillo-like helical domain-containing protein 3; Involved in GBF1 recruitment, Golgi maintenance and protein secretion. | Serine/threonine-protein kinase tousled-like 2; Serine/threonine-protein kinase involved in the process of chromatin assembly and probably also DNA replication, transcription, repair, and chromosome segregation. Phosphorylates the chromatin assembly factors ASF1A AND ASF1B. Phosphorylation of ASF1A prevents its proteasome-mediated degradation, thereby enhancing chromatin assembly. Negative regulator of amino acid starvation-induced autophagy. | 0.520 |
| ARMH3 | TMUB2 | ENSP00000359050 | ENSP00000444565 | Armadillo-like helical domain-containing protein 3; Involved in GBF1 recruitment, Golgi maintenance and protein secretion. | Transmembrane and ubiquitin like domain containing 2. | 0.566 |
| ARMH3 | TTC31 | ENSP00000359050 | ENSP00000233623 | Armadillo-like helical domain-containing protein 3; Involved in GBF1 recruitment, Golgi maintenance and protein secretion. | Tetratricopeptide repeat domain 31. | 0.584 |
| CNOT10 | ARMH3 | ENSP00000399862 | ENSP00000359050 | CCR4-NOT transcription complex subunit 10; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex. | Armadillo-like helical domain-containing protein 3; Involved in GBF1 recruitment, Golgi maintenance and protein secretion. | 0.561 |
| CNOT10 | COG7 | ENSP00000399862 | ENSP00000305442 | CCR4-NOT transcription complex subunit 10; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex. | Conserved oligomeric Golgi complex subunit 7; Required for normal Golgi function. | 0.463 |
| CNOT10 | NOL7 | ENSP00000399862 | ENSP00000405674 | CCR4-NOT transcription complex subunit 10; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex. | Nucleolar protein 7. | 0.569 |
| CNOT10 | SLC4A1AP | ENSP00000399862 | ENSP00000479964 | CCR4-NOT transcription complex subunit 10; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex. | Kanadaptin; Solute carrier family 4 member 1 adaptor protein. | 0.498 |
| CNOT10 | TLK2 | ENSP00000399862 | ENSP00000316512 | CCR4-NOT transcription complex subunit 10; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex. | Serine/threonine-protein kinase tousled-like 2; Serine/threonine-protein kinase involved in the process of chromatin assembly and probably also DNA replication, transcription, repair, and chromosome segregation. Phosphorylates the chromatin assembly factors ASF1A AND ASF1B. Phosphorylation of ASF1A prevents its proteasome-mediated degradation, thereby enhancing chromatin assembly. Negative regulator of amino acid starvation-induced autophagy. | 0.498 |
| CNOT10 | TMUB2 | ENSP00000399862 | ENSP00000444565 | CCR4-NOT transcription complex subunit 10; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4-NOT complex. | Transmembrane and ubiquitin like domain containing 2. | 0.480 |
| COG7 | ARMH3 | ENSP00000305442 | ENSP00000359050 | Conserved oligomeric Golgi complex subunit 7; Required for normal Golgi function. | Armadillo-like helical domain-containing protein 3; Involved in GBF1 recruitment, Golgi maintenance and protein secretion. | 0.554 |
