Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BPY2Basic charge Y-linked 2. (106 aa)    
Predicted Functional Partners:
CDY1
Testis-specific chromodomain protein Y 1; Has histone acetyltransferase activity, with a preference for histone H4.
      
 0.965
CDY2A
Testis-specific chromodomain protein Y 2; May have histone acetyltransferase activity.
      
 0.945
VCY1B
Testis-specific basic protein Y 1; May mediate a process in spermatogenesis or may play a role in sex ratio distortion; Belongs to the VCX/VCY family.
      
 0.942
VCY
Variable charge Y-linked.
      
 0.941
DAZ1
Deleted in azoospermia protein 1; RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. Promotes germ-cell progression to meiosis and formation of haploid germ cells.
   
  
 0.941
PRY
PTPN13-like protein, Y-linked; PTPN13 like Y-linked.
      
 0.930
PRY2
PTPN13 like Y-linked 2.
      
 0.929
PRYP3
PTPN13 like Y-linked pseudogene 3.
      
 0.927
CDY2B
Chromodomain Y-linked 2B.
      
 0.920
DAZ2
Deleted in azoospermia 2.
   
  
 0.896
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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