| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C1orf109 | C5orf22 | ENSP00000350704 | ENSP00000326879 | Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition. | UPF0489 protein C5orf22; Chromosome 5 open reading frame 22; Belongs to the UPF0489 family. | 0.686 |
| C1orf109 | CWC25 | ENSP00000350704 | ENSP00000478070 | Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition. | Pre-mRNA-splicing factor CWC25 homolog; Involved in pre-mRNA splicing as component of the spliceosome; Belongs to the CWC25 family. | 0.802 |
| C1orf109 | FBXO47 | ENSP00000350704 | ENSP00000367319 | Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition. | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | 0.723 |
| C1orf109 | UGT3A1 | ENSP00000350704 | ENSP00000274278 | Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition. | UDP-glucuronosyltransferase 3A1; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity); Belongs to the UDP-glycosyltransferase family. | 0.686 |
| C1orf109 | UGT3A2 | ENSP00000350704 | ENSP00000282507 | Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition. | UDP-glucuronosyltransferase 3A2; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity); Belongs to the UDP-glycosyltransferase family. | 0.686 |
| C5orf22 | C1orf109 | ENSP00000326879 | ENSP00000350704 | UPF0489 protein C5orf22; Chromosome 5 open reading frame 22; Belongs to the UPF0489 family. | Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition. | 0.686 |
| C5orf22 | CWC25 | ENSP00000326879 | ENSP00000478070 | UPF0489 protein C5orf22; Chromosome 5 open reading frame 22; Belongs to the UPF0489 family. | Pre-mRNA-splicing factor CWC25 homolog; Involved in pre-mRNA splicing as component of the spliceosome; Belongs to the CWC25 family. | 0.625 |
| C5orf22 | ELOF1 | ENSP00000326879 | ENSP00000465765 | UPF0489 protein C5orf22; Chromosome 5 open reading frame 22; Belongs to the UPF0489 family. | Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. | 0.854 |
| C5orf22 | FBXO47 | ENSP00000326879 | ENSP00000367319 | UPF0489 protein C5orf22; Chromosome 5 open reading frame 22; Belongs to the UPF0489 family. | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | 0.618 |
| C5orf22 | OSM | ENSP00000326879 | ENSP00000215781 | UPF0489 protein C5orf22; Chromosome 5 open reading frame 22; Belongs to the UPF0489 family. | Oncostatin-M; Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity). Belongs to the LIF/OSM family. | 0.776 |
| C5orf22 | PQBP1 | ENSP00000326879 | ENSP00000498362 | UPF0489 protein C5orf22; Chromosome 5 open reading frame 22; Belongs to the UPF0489 family. | Polyglutamine-binding protein 1; Intrinsically disordered protein that acts as a scaffold, and which is involved in different processes, such as pre-mRNA splicing, transcription regulation, innate immunity and neuron development. Interacts with splicing-related factors via the intrinsically disordered region and regulates alternative splicing of target pre-mRNA species. May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-in [...] | 0.819 |
| C5orf22 | SURF2 | ENSP00000326879 | ENSP00000361032 | UPF0489 protein C5orf22; Chromosome 5 open reading frame 22; Belongs to the UPF0489 family. | Surfeit 2; Belongs to the SURF2 family. | 0.589 |
| C5orf22 | UGT3A1 | ENSP00000326879 | ENSP00000274278 | UPF0489 protein C5orf22; Chromosome 5 open reading frame 22; Belongs to the UPF0489 family. | UDP-glucuronosyltransferase 3A1; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity); Belongs to the UDP-glycosyltransferase family. | 0.597 |
| C5orf22 | UGT3A2 | ENSP00000326879 | ENSP00000282507 | UPF0489 protein C5orf22; Chromosome 5 open reading frame 22; Belongs to the UPF0489 family. | UDP-glucuronosyltransferase 3A2; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity); Belongs to the UDP-glycosyltransferase family. | 0.597 |
| C5orf22 | WBP11 | ENSP00000326879 | ENSP00000261167 | UPF0489 protein C5orf22; Chromosome 5 open reading frame 22; Belongs to the UPF0489 family. | WW domain-binding protein 11; Activates pre-mRNA splicing. May inhibit PP1 phosphatase activity. | 0.907 |
| CWC25 | C1orf109 | ENSP00000478070 | ENSP00000350704 | Pre-mRNA-splicing factor CWC25 homolog; Involved in pre-mRNA splicing as component of the spliceosome; Belongs to the CWC25 family. | Uncharacterized protein C1orf109; May promote cancer cell proliferation by controlling the G1 to S phase transition. | 0.802 |
| CWC25 | C5orf22 | ENSP00000478070 | ENSP00000326879 | Pre-mRNA-splicing factor CWC25 homolog; Involved in pre-mRNA splicing as component of the spliceosome; Belongs to the CWC25 family. | UPF0489 protein C5orf22; Chromosome 5 open reading frame 22; Belongs to the UPF0489 family. | 0.625 |
| CWC25 | UGT3A1 | ENSP00000478070 | ENSP00000274278 | Pre-mRNA-splicing factor CWC25 homolog; Involved in pre-mRNA splicing as component of the spliceosome; Belongs to the CWC25 family. | UDP-glucuronosyltransferase 3A1; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity); Belongs to the UDP-glycosyltransferase family. | 0.686 |
| CWC25 | UGT3A2 | ENSP00000478070 | ENSP00000282507 | Pre-mRNA-splicing factor CWC25 homolog; Involved in pre-mRNA splicing as component of the spliceosome; Belongs to the CWC25 family. | UDP-glucuronosyltransferase 3A2; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity); Belongs to the UDP-glycosyltransferase family. | 0.686 |
| ELOF1 | C5orf22 | ENSP00000465765 | ENSP00000326879 | Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. | UPF0489 protein C5orf22; Chromosome 5 open reading frame 22; Belongs to the UPF0489 family. | 0.854 |