Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CDRT15CMT1A duplicated region transcript 15. (188 aa)    
Predicted Functional Partners:
CDRT15L2
CMT1A duplicated region transcript 15 like 2.
   
 
0.920
MAP4K5
Mitogen-activated protein kinase kinase kinase kinase 5; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
    
   0.836
NUDT8
Nucleoside diphosphate-linked moiety X motif 8; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
    
   0.771
DPY19L1
Probable C-mannosyltransferase DPY19L1; Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.
    
   0.630
OR56A5
Olfactory receptor 56A5; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.591
TVP23B
Trans-golgi network vesicle protein 23 homolog B; Belongs to the TVP23 family.
      
 0.571
OR5D13
Olfactory receptor 5D13; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.547
CDRT4
CMT1A duplicated region transcript 4.
      
 0.540
SMCO2
Single-pass membrane protein with coiled-coil domains 2.
      
 0.537
HS3ST3B1
Heparan sulfate glucosamine 3-O-sulfotransferase 3B1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to antico [...]
      
 0.536
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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