Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
CDRT4CMT1A duplicated region transcript 4. (152 aa)    
Predicted Functional Partners:
TVP23C-CDRT4
Golgi apparatus membrane protein TVP23 homolog; TVP23C-CDRT4 readthrough.
 
 
  
 0.848
TVP23C
Trans-golgi network vesicle protein 23 homolog C; Belongs to the TVP23 family.
 
 
  
 0.718
VAC14
Protein VAC14 homolog; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts as a positive activator of PIKfyve kinase activity. Also required to maintain normal levels of phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 5-phosphate (PtdIns(5)P). Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes.
    
   0.688
SLC35G6
Solute carrier family 35 member G6.
   
    0.561
TVP23B
Trans-golgi network vesicle protein 23 homolog B; Belongs to the TVP23 family.
 
    
 0.550
CDRT15
CMT1A duplicated region transcript 15.
      
 0.540
STIMATE-MUSTN1
STIMATE-MUSTN1 readthrough.
      
 0.531
TEKT3
Tektin-3; May be a structural component of the sperm flagellum. Required for normal sperm mobility.
   
  
 0.488
TMEM225B
Transmembrane protein 225B.
   
  
 0.478
H0YIS7_HUMAN
RNASEK-C17orf49 readthrough.
      
 0.470
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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