Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CFAP47Cilia and flagella associated protein 47. (3187 aa)    
Predicted Functional Partners:
CFAP69
Cilia- and flagella-associated protein 69; Cilium- and flagellum-associated protein. In the olfactory epithelium, regulates the speed of activation and termination of the odor response and thus contributes to the robustness of olfactory transduction pathways (By similarity). Required for sperm flagellum assembly and stability.
   
 
 0.863
CFAP70
Cilia and flagella associated protein 70; Belongs to the CFAP70 family.
   
 
 0.862
LRRC43
Leucine-rich repeat-containing protein 43; Leucine rich repeat containing 43.
   
 
 0.841
HYDIN
Hydrocephalus-inducing protein homolog; Required for ciliary motility.
   
 
 0.816
CFAP54
Cilia- and flagella-associated protein 54; Required for assembly and function of cilia and flagella.
   
 
 0.779
CFAP99
Cilia and flagella associated protein 99.
   
 
 0.776
LRGUK
Leucine-rich repeat and guanylate kinase domain-containing protein; Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis.
   
 
 0.768
DLEC1
Deleted in lung and esophageal cancer protein 1; May act as a tumor suppressor by inhibiting cell proliferation.
   
 
 0.768
KIF9
Kinesin-like protein KIF9; Kinesin family member 9.
   
 
 0.764
SPATA17
Spermatogenesis-associated protein 17; Spermatogenesis associated 17.
   
 
 0.761
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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