COG3 protein (human) - STRING interaction network

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Score

COG3

Conserved oligomeric Golgi complex subunit 3; Involved in ER-Golgi transport. (828 aa)

Predicted Functional Partners:

COG5

0.999

COG1

0.999

COG7

0.999

COG4

0.999

COG2

0.999

COG6

0.999

COG8

0.999

VSIG2

0.985

SCFD1

0.946

CD274

0.926

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD274	COG1	ENSP00000370989	ENSP00000299886	Programmed cell death 1 ligand 1; Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response. Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10).	Conserved oligomeric Golgi complex subunit 1; Required for normal Golgi function.	0.880
CD274	COG2	ENSP00000370989	ENSP00000355629	Programmed cell death 1 ligand 1; Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response. Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10).	Conserved oligomeric Golgi complex subunit 2; Required for normal Golgi morphology and function; Belongs to the COG2 family.	0.774
CD274	COG3	ENSP00000370989	ENSP00000258654	Programmed cell death 1 ligand 1; Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response. Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10).	Conserved oligomeric Golgi complex subunit 3; Involved in ER-Golgi transport.	0.926
CD274	COG4	ENSP00000370989	ENSP00000315775	Programmed cell death 1 ligand 1; Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response. Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10).	Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1. Belongs to the COG4 family.	0.463
CD274	COG5	ENSP00000370989	ENSP00000297135	Programmed cell death 1 ligand 1; Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response. Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10).	Conserved oligomeric Golgi complex subunit 5; Required for normal Golgi function; Belongs to the COG5 family.	0.881
CD274	COG7	ENSP00000370989	ENSP00000305442	Programmed cell death 1 ligand 1; Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response. Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10).	Conserved oligomeric Golgi complex subunit 7; Required for normal Golgi function.	0.828
CD274	COG8	ENSP00000370989	ENSP00000497669	Programmed cell death 1 ligand 1; Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response. Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10).	Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function.	0.868
COG1	CD274	ENSP00000299886	ENSP00000370989	Conserved oligomeric Golgi complex subunit 1; Required for normal Golgi function.	Programmed cell death 1 ligand 1; Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response. Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10).	0.880
COG1	COG2	ENSP00000299886	ENSP00000355629	Conserved oligomeric Golgi complex subunit 1; Required for normal Golgi function.	Conserved oligomeric Golgi complex subunit 2; Required for normal Golgi morphology and function; Belongs to the COG2 family.	0.999
COG1	COG3	ENSP00000299886	ENSP00000258654	Conserved oligomeric Golgi complex subunit 1; Required for normal Golgi function.	Conserved oligomeric Golgi complex subunit 3; Involved in ER-Golgi transport.	0.999
COG1	COG4	ENSP00000299886	ENSP00000315775	Conserved oligomeric Golgi complex subunit 1; Required for normal Golgi function.	Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1. Belongs to the COG4 family.	0.999
COG1	COG5	ENSP00000299886	ENSP00000297135	Conserved oligomeric Golgi complex subunit 1; Required for normal Golgi function.	Conserved oligomeric Golgi complex subunit 5; Required for normal Golgi function; Belongs to the COG5 family.	0.999
COG1	COG6	ENSP00000299886	ENSP00000397441	Conserved oligomeric Golgi complex subunit 1; Required for normal Golgi function.	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function; Belongs to the COG6 family.	0.999
COG1	COG7	ENSP00000299886	ENSP00000305442	Conserved oligomeric Golgi complex subunit 1; Required for normal Golgi function.	Conserved oligomeric Golgi complex subunit 7; Required for normal Golgi function.	0.999
COG1	COG8	ENSP00000299886	ENSP00000497669	Conserved oligomeric Golgi complex subunit 1; Required for normal Golgi function.	Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function.	0.999
COG1	SCFD1	ENSP00000299886	ENSP00000390783	Conserved oligomeric Golgi complex subunit 1; Required for normal Golgi function.	Sec1 family domain-containing protein 1; Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi (By similarity).	0.512
COG2	CD274	ENSP00000355629	ENSP00000370989	Conserved oligomeric Golgi complex subunit 2; Required for normal Golgi morphology and function; Belongs to the COG2 family.	Programmed cell death 1 ligand 1; Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response. Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10).	0.774
COG2	COG1	ENSP00000355629	ENSP00000299886	Conserved oligomeric Golgi complex subunit 2; Required for normal Golgi morphology and function; Belongs to the COG2 family.	Conserved oligomeric Golgi complex subunit 1; Required for normal Golgi function.	0.999
COG2	COG3	ENSP00000355629	ENSP00000258654	Conserved oligomeric Golgi complex subunit 2; Required for normal Golgi morphology and function; Belongs to the COG2 family.	Conserved oligomeric Golgi complex subunit 3; Involved in ER-Golgi transport.	0.999
COG2	COG4	ENSP00000355629	ENSP00000315775	Conserved oligomeric Golgi complex subunit 2; Required for normal Golgi morphology and function; Belongs to the COG2 family.	Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1. Belongs to the COG4 family.	0.999