Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CPB1Carboxypeptidase B1; Belongs to the peptidase M14 family. (417 aa)    
Predicted Functional Partners:
CPA1
Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro; Belongs to the peptidase M14 family.
  
  
0.998
CTRB2
Chymotrypsinogen B2; Belongs to the peptidase S1 family.
   
 
 0.972
CTRB1
Chymotrypsinogen B1; Belongs to the peptidase S1 family.
   
 
 0.972
CELA3B
Chymotrypsin-like elastase family member 3B; Efficient protease with alanine specificity but only little elastolytic activity.
   
 
 0.966
CELA3A
Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity; Belongs to the peptidase S1 family. Elastase subfamily.
   
 
 0.963
CEL
Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs (By similarity). Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins. Belongs to the type-B carboxylesterase/ [...]
   
  
 0.933
CTRL
Chymotrypsin-like protease CTRL-1; Chymotrypsin like; Belongs to the peptidase S1 family.
   
 
 0.930
CELA2A
Chymotrypsin-like elastase family member 2A; Acts upon elastin.
   
 
 0.929
CPB2
Carboxypeptidase B2; Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. Belongs to the peptidase M14 family.
  
 
0.914
CTRC
Chymotrypsin-C; Regulates activation and degradation of trypsinogens and procarboxypeptidases by targeting specific cleavage sites within their zymogen precursors. Has chymotrypsin-type protease activity and hypocalcemic activity.
   
 
 0.913
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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