Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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CXorf58Putative uncharacterized protein CXorf58; Chromosome X open reading frame 58. (332 aa)    
Predicted Functional Partners:
GDE1
Glycerophosphodiester phosphodiesterase 1; Has glycerophosphoinositol phosphodiesterase activity. Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Has little or no activity towards glycerophosphocholine. GDE1 activity can be modulated by G-protein signaling pathways (By similarity).
    
   0.831
C19orf81
Putative uncharacterized protein C19orf81; Chromosome 19 open reading frame 81.
   
  
 0.756
AXDND1
Axonemal dynein light chain domain containing 1.
  
  
 0.687
SMLR1
Small leucine rich protein 1.
      
 0.663
C7orf25
UPF0415 protein C7orf25; Chromosome 7 open reading frame 25; Belongs to the UPF0415 family.
      
 0.655
RSRP1
Arginine and serine rich protein 1.
      
 0.537
CFAP46
Cilia- and flagella-associated protein 46; As part of the central apparatus of the cilium axoneme plays a role in cilium movement.
   
  
 0.517
ZBTB21
Zinc finger and BTB domain-containing protein 21; Acts as a transcription repressor.
      
 0.470
SPR
Sepiapterin reductase; Catalyzes the final one or two reductions in tetra- hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin; Belongs to the sepiapterin reductase family.
      
 0.435
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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