DEFB107A protein (human) - STRING interaction network

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Score

DEFB107A

Beta-defensin 107; Has antibacterial activity. (70 aa)

Predicted Functional Partners:

DEFB106B

0.924

DEFB105A

0.922

DEFB108B

0.862

DEFB106A

0.862

DEFB104A

0.841

DEFB103A

0.831

DEFB1

0.816

DEFB110

0.807

SPAG11B

0.780

DEFB113

0.777

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DEFB1	DEFB103A	ENSP00000297439	ENSP00000320951	Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.	Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed.	0.994
DEFB1	DEFB104A	ENSP00000297439	ENSP00000320813	Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.	Beta-defensin 104; Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103; Belongs to the beta-defensin family.	0.953
DEFB1	DEFB105A	ENSP00000297439	ENSP00000334330	Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.	Beta-defensin 105; Has antibacterial activity.	0.911
DEFB1	DEFB106A	ENSP00000297439	ENSP00000335307	Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.	Defensin beta 106A.	0.569
DEFB1	DEFB106B	ENSP00000297439	ENSP00000334364	Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.	Beta-defensin 106; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2. Belongs to the beta-defensin family.	0.885
DEFB1	DEFB107A	ENSP00000297439	ENSP00000334681	Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.	Beta-defensin 107; Has antibacterial activity.	0.816
DEFB1	DEFB108B	ENSP00000297439	ENSP00000333234	Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.	Beta-defensin 108B; Has antibacterial activity.	0.815
DEFB1	DEFB110	ENSP00000297439	ENSP00000360190	Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.	Beta-defensin 110; Has antibacterial activity.	0.687
DEFB1	DEFB113	ENSP00000297439	ENSP00000381703	Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.	Beta-defensin 113; Has antibacterial activity; Belongs to the beta-defensin family.	0.643
DEFB1	SPAG11B	ENSP00000297439	ENSP00000381480	Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.	Sperm associated antigen 11B.	0.530
DEFB103A	DEFB1	ENSP00000320951	ENSP00000297439	Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed.	Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.	0.994
DEFB103A	DEFB104A	ENSP00000320951	ENSP00000320813	Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed.	Beta-defensin 104; Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103; Belongs to the beta-defensin family.	0.974
DEFB103A	DEFB105A	ENSP00000320951	ENSP00000334330	Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed.	Beta-defensin 105; Has antibacterial activity.	0.874
DEFB103A	DEFB106A	ENSP00000320951	ENSP00000335307	Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed.	Defensin beta 106A.	0.662
DEFB103A	DEFB106B	ENSP00000320951	ENSP00000334364	Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed.	Beta-defensin 106; Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2. Belongs to the beta-defensin family.	0.877
DEFB103A	DEFB107A	ENSP00000320951	ENSP00000334681	Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed.	Beta-defensin 107; Has antibacterial activity.	0.831
DEFB103A	DEFB108B	ENSP00000320951	ENSP00000333234	Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed.	Beta-defensin 108B; Has antibacterial activity.	0.815
DEFB103A	DEFB110	ENSP00000320951	ENSP00000360190	Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed.	Beta-defensin 110; Has antibacterial activity.	0.696
DEFB103A	DEFB113	ENSP00000320951	ENSP00000381703	Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed.	Beta-defensin 113; Has antibacterial activity; Belongs to the beta-defensin family.	0.652
DEFB103A	SPAG11B	ENSP00000320951	ENSP00000381480	Beta-defensin 103; Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed.	Sperm associated antigen 11B.	0.742