DEFB135 protein (human) - STRING interaction network

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Score

DEFB135

Beta-defensin 135; Has antibacterial activity; Belongs to the beta-defensin family. (77 aa)

Predicted Functional Partners:

DEFB134

0.916

DEFB124

0.897

DEFB128

0.895

DEFB125

0.894

DEFB136

0.870

DEFB127

0.853

DEFB114

0.831

DEFB130A

0.820

DEFB130B

0.817

DEFB119

0.785

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DEFB114	DEFB119	ENSP00000312702	ENSP00000365492	Beta-defensin 114; Has a salt-sensitive antimicrobial activity against Gram- negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality.	Defensin beta 119.	0.571
DEFB114	DEFB124	ENSP00000312702	ENSP00000326309	Beta-defensin 114; Has a salt-sensitive antimicrobial activity against Gram- negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality.	Beta-defensin 124; Has antibacterial activity; Belongs to the beta-defensin family.	0.836
DEFB114	DEFB125	ENSP00000312702	ENSP00000371847	Beta-defensin 114; Has a salt-sensitive antimicrobial activity against Gram- negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality.	Beta-defensin 125; Has antibacterial activity; Belongs to the beta-defensin family.	0.834
DEFB114	DEFB127	ENSP00000312702	ENSP00000371825	Beta-defensin 114; Has a salt-sensitive antimicrobial activity against Gram- negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality.	Beta-defensin 127; Has antibacterial activity.	0.864
DEFB114	DEFB128	ENSP00000312702	ENSP00000335382	Beta-defensin 114; Has a salt-sensitive antimicrobial activity against Gram- negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality.	Beta-defensin 128; Has antibacterial activity; Belongs to the beta-defensin family.	0.816
DEFB114	DEFB130A	ENSP00000312702	ENSP00000382951	Beta-defensin 114; Has a salt-sensitive antimicrobial activity against Gram- negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality.	Beta-defensin 130A; Antimicrobial host-defense peptide. Has an antiplasmodial activity.	0.559
DEFB114	DEFB130B	ENSP00000312702	ENSP00000392568	Beta-defensin 114; Has a salt-sensitive antimicrobial activity against Gram- negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality.	Defensin beta 130B.	0.738
DEFB114	DEFB134	ENSP00000312702	ENSP00000435010	Beta-defensin 114; Has a salt-sensitive antimicrobial activity against Gram- negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality.	Beta-defensin 134; Has antibacterial activity; Belongs to the beta-defensin family.	0.830
DEFB114	DEFB135	ENSP00000312702	ENSP00000371643	Beta-defensin 114; Has a salt-sensitive antimicrobial activity against Gram- negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality.	Beta-defensin 135; Has antibacterial activity; Belongs to the beta-defensin family.	0.831
DEFB114	DEFB136	ENSP00000312702	ENSP00000371644	Beta-defensin 114; Has a salt-sensitive antimicrobial activity against Gram- negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality.	Beta-defensin 136; Has antibacterial activity; Belongs to the beta-defensin family.	0.733
DEFB119	DEFB114	ENSP00000365492	ENSP00000312702	Defensin beta 119.	Beta-defensin 114; Has a salt-sensitive antimicrobial activity against Gram- negative bacteria, including E.coli, Gram-positive, including S.aureus, and fungi, including C.albicans. Binds to and neutralizes bacterial lipopolysaccharides (LPS), abolishing TNF production by macrophages challenged with LPS. Rescues the LPS-induced reduction of sperm motility in vitro and may protect from LPS-induced lethality.	0.571
DEFB119	DEFB124	ENSP00000365492	ENSP00000326309	Defensin beta 119.	Beta-defensin 124; Has antibacterial activity; Belongs to the beta-defensin family.	0.802
DEFB119	DEFB125	ENSP00000365492	ENSP00000371847	Defensin beta 119.	Beta-defensin 125; Has antibacterial activity; Belongs to the beta-defensin family.	0.812
DEFB119	DEFB127	ENSP00000365492	ENSP00000371825	Defensin beta 119.	Beta-defensin 127; Has antibacterial activity.	0.786
DEFB119	DEFB128	ENSP00000365492	ENSP00000335382	Defensin beta 119.	Beta-defensin 128; Has antibacterial activity; Belongs to the beta-defensin family.	0.754
DEFB119	DEFB130A	ENSP00000365492	ENSP00000382951	Defensin beta 119.	Beta-defensin 130A; Antimicrobial host-defense peptide. Has an antiplasmodial activity.	0.664
DEFB119	DEFB130B	ENSP00000365492	ENSP00000392568	Defensin beta 119.	Defensin beta 130B.	0.527
DEFB119	DEFB134	ENSP00000365492	ENSP00000435010	Defensin beta 119.	Beta-defensin 134; Has antibacterial activity; Belongs to the beta-defensin family.	0.596
DEFB119	DEFB135	ENSP00000365492	ENSP00000371643	Defensin beta 119.	Beta-defensin 135; Has antibacterial activity; Belongs to the beta-defensin family.	0.785
DEFB119	DEFB136	ENSP00000365492	ENSP00000371644	Defensin beta 119.	Beta-defensin 136; Has antibacterial activity; Belongs to the beta-defensin family.	0.671