Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
DMRTC1BDoublesex- and mab-3-related transcription factor C1; DMRT like family C1B; Belongs to the DMRT family. (192 aa)    
Predicted Functional Partners:
FAM236A
Family with sequence similarity 235 member A.
   
    0.978
DMRTC1
DMRT like family C1.
   
   
0.782
CXorf49B
Chromosome X open reading frame 49B.
    
 
 0.570
CXorf49
Uncharacterized protein CXorf49; Chromosome X open reading frame 49.
    
 
 0.568
EFNA4
Ephrin-A4; Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. May play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils.
    
   0.457
PNMA6A
Paraneoplastic antigen-like protein 6A; PNMA family member 6A; Belongs to the PNMA family.
   
 
 0.413
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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