| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCDC113 | CCDC65 | ENSP00000219299 | ENSP00000312706 | Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation. | Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. Belongs to the DRC2 family. | 0.983 |
| CCDC113 | CFAP43 | ENSP00000219299 | ENSP00000349568 | Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation. | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function. | 0.976 |
| CCDC113 | CFAP52 | ENSP00000219299 | ENSP00000339449 | Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation. | Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family. | 0.895 |
| CCDC113 | EFHB | ENSP00000219299 | ENSP00000295824 | Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation. | EF-hand domain-containing family member B; Cytosolic sensor for calcium, modulates the interaction of STIM1 and ORAI1 upon store depletion, the activation of store-operated Ca(2+) entry (SOCE) and NFAT translocation from cytosol to nucleus. | 0.966 |
| CCDC113 | EFHC1 | ENSP00000219299 | ENSP00000360107 | Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation. | EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death. | 0.950 |
| CCDC113 | EFHC2 | ENSP00000219299 | ENSP00000404232 | Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation. | EF-hand domain-containing family member C2; EF-hand domain containing 2. | 0.925 |
| CCDC113 | ENKUR | ENSP00000219299 | ENSP00000331044 | Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation. | Enkurin; Adapter that functions to localize a calcium-sensitive signal transduction machinery in sperm to a calcium-permeable ion channel. | 0.977 |
| CCDC113 | MNS1 | ENSP00000219299 | ENSP00000260453 | Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation. | Meiosis-specific nuclear structural protein 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis; Belongs to the MNS1 family. | 0.840 |
| CCDC113 | TEKT2 | ENSP00000219299 | ENSP00000207457 | Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation. | Tektin-2; Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. | 0.835 |
| CCDC65 | CCDC113 | ENSP00000312706 | ENSP00000219299 | Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. Belongs to the DRC2 family. | Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation. | 0.983 |
| CCDC65 | CFAP43 | ENSP00000312706 | ENSP00000349568 | Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. Belongs to the DRC2 family. | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function. | 0.980 |
| CCDC65 | CFAP52 | ENSP00000312706 | ENSP00000339449 | Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. Belongs to the DRC2 family. | Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family. | 0.949 |
| CCDC65 | EFHB | ENSP00000312706 | ENSP00000295824 | Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. Belongs to the DRC2 family. | EF-hand domain-containing family member B; Cytosolic sensor for calcium, modulates the interaction of STIM1 and ORAI1 upon store depletion, the activation of store-operated Ca(2+) entry (SOCE) and NFAT translocation from cytosol to nucleus. | 0.969 |
| CCDC65 | EFHC1 | ENSP00000312706 | ENSP00000360107 | Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. Belongs to the DRC2 family. | EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death. | 0.954 |
| CCDC65 | EFHC2 | ENSP00000312706 | ENSP00000404232 | Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. Belongs to the DRC2 family. | EF-hand domain-containing family member C2; EF-hand domain containing 2. | 0.934 |
| CCDC65 | ENKUR | ENSP00000312706 | ENSP00000331044 | Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. Belongs to the DRC2 family. | Enkurin; Adapter that functions to localize a calcium-sensitive signal transduction machinery in sperm to a calcium-permeable ion channel. | 0.983 |
| CCDC65 | MNS1 | ENSP00000312706 | ENSP00000260453 | Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. Belongs to the DRC2 family. | Meiosis-specific nuclear structural protein 1; May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis; Belongs to the MNS1 family. | 0.895 |
| CCDC65 | TEKT2 | ENSP00000312706 | ENSP00000207457 | Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. Belongs to the DRC2 family. | Tektin-2; Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. | 0.882 |
| CFAP43 | CCDC113 | ENSP00000349568 | ENSP00000219299 | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function. | Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation. | 0.976 |
| CFAP43 | CCDC65 | ENSP00000349568 | ENSP00000312706 | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function. | Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. Belongs to the DRC2 family. | 0.980 |
