STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCDHB1Protocadherin beta-1; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. (818 aa)    
Predicted Functional Partners:
CDKL1
Cyclin-dependent kinase-like 1; Cyclin dependent kinase like 1; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
   
  
 0.550
OR2S2
Olfactory receptor 2S2; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.483
OR4K1
Olfactory receptor 4K1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.450
CNR2
Cannabinoid receptor 2; Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis.
  
  
 0.448
AMY2B
Amylase alpha 2B; Belongs to the glycosyl hydrolase 13 family.
   
 
 0.444
TMEM211
Transmembrane protein 211.
    
 
 0.444
MC2R
Adrenocorticotropic hormone receptor; Receptor for corticotropin (ACTH). This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase (cAMP). Belongs to the G-protein coupled receptor 1 family.
   
    0.434
OR4K2
Olfactory receptor 4K2; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.410
AMY1B
Amylase alpha 1B; Belongs to the glycosyl hydrolase 13 family.
   
 
 0.407
AMY2A
Pancreatic alpha-amylase; Amylase alpha 2A.
   
 
 0.403
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.