Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCDC136 | IFT122 | ENSP00000297788 | ENSP00000296266 | Coiled-coil domain-containing protein 136; May play a role in acrosome formation in spermatogenesis and in fertilization. | Intraflagellar transport protein 122 homolog; As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is required in ciliogenesis and ciliary protein trafficking. Involved in cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling. Required to recruit TULP3 to primary cilia (By similarity). | 0.432 |
| CCDC136 | MEGF6 | ENSP00000297788 | ENSP00000348982 | Coiled-coil domain-containing protein 136; May play a role in acrosome formation in spermatogenesis and in fertilization. | Multiple epidermal growth factor-like domains protein 6; Multiple EGF like domains 6. | 0.624 |
| CD3D | MEGF6 | ENSP00000300692 | ENSP00000348982 | T-cell surface glycoprotein CD3 delta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of [...] | Multiple epidermal growth factor-like domains protein 6; Multiple EGF like domains 6. | 0.536 |
| CD3D | WRAP73 | ENSP00000300692 | ENSP00000270708 | T-cell surface glycoprotein CD3 delta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of [...] | WD repeat-containing protein WRAP73; The SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome. Required for the centrosomal localization of SSX2IP and normal mitotic bipolar spindle morphology. Required for the targeting of centriole satellite proteins to centrosomes such as of PCM1, SSX2IP, CEP290 and PIBF1/CEP90. Required for ciliogenesis and involved in the removal of the CEP97:CCP110 complex from the mother centriole. Involved in ciliary vesicle formation at the mother centriole and required for the docking of vesicles to the basal bo [...] | 0.633 |
| CD3D | ZBTB40 | ENSP00000300692 | ENSP00000384527 | T-cell surface glycoprotein CD3 delta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of [...] | Zinc finger and BTB domain-containing protein 40; May be involved in transcriptional regulation. | 0.550 |
| CRIM1 | MEGF6 | ENSP00000280527 | ENSP00000348982 | Processed cysteine-rich motor neuron 1 protein; May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival. May play a role in capillary formation and maintenance during angiogenesis. Modulates BMP activity by affecting its processing and delivery to the cell surface. | Multiple epidermal growth factor-like domains protein 6; Multiple EGF like domains 6. | 0.461 |
| IFT122 | CCDC136 | ENSP00000296266 | ENSP00000297788 | Intraflagellar transport protein 122 homolog; As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is required in ciliogenesis and ciliary protein trafficking. Involved in cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling. Required to recruit TULP3 to primary cilia (By similarity). | Coiled-coil domain-containing protein 136; May play a role in acrosome formation in spermatogenesis and in fertilization. | 0.432 |
| IFT122 | MEGF6 | ENSP00000296266 | ENSP00000348982 | Intraflagellar transport protein 122 homolog; As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is required in ciliogenesis and ciliary protein trafficking. Involved in cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling. Required to recruit TULP3 to primary cilia (By similarity). | Multiple epidermal growth factor-like domains protein 6; Multiple EGF like domains 6. | 0.568 |
| MEGF6 | CCDC136 | ENSP00000348982 | ENSP00000297788 | Multiple epidermal growth factor-like domains protein 6; Multiple EGF like domains 6. | Coiled-coil domain-containing protein 136; May play a role in acrosome formation in spermatogenesis and in fertilization. | 0.624 |
| MEGF6 | CD3D | ENSP00000348982 | ENSP00000300692 | Multiple epidermal growth factor-like domains protein 6; Multiple EGF like domains 6. | T-cell surface glycoprotein CD3 delta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of [...] | 0.536 |
| MEGF6 | CRIM1 | ENSP00000348982 | ENSP00000280527 | Multiple epidermal growth factor-like domains protein 6; Multiple EGF like domains 6. | Processed cysteine-rich motor neuron 1 protein; May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival. May play a role in capillary formation and maintenance during angiogenesis. Modulates BMP activity by affecting its processing and delivery to the cell surface. | 0.461 |
| MEGF6 | IFT122 | ENSP00000348982 | ENSP00000296266 | Multiple epidermal growth factor-like domains protein 6; Multiple EGF like domains 6. | Intraflagellar transport protein 122 homolog; As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is required in ciliogenesis and ciliary protein trafficking. Involved in cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling. Required to recruit TULP3 to primary cilia (By similarity). | 0.568 |
| MEGF6 | MFAP5 | ENSP00000348982 | ENSP00000352455 | Multiple epidermal growth factor-like domains protein 6; Multiple EGF like domains 6. | Microfibrillar-associated protein 5; May play a role in hematopoiesis. In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel integrity (By similarity). Component of the elastin-associated microfibrils. | 0.719 |
| MEGF6 | MORN1 | ENSP00000348982 | ENSP00000367792 | Multiple epidermal growth factor-like domains protein 6; Multiple EGF like domains 6. | MORN repeat containing 1. | 0.462 |
| MEGF6 | RPL36A-HNRNPH2 | ENSP00000348982 | ENSP00000386655 | Multiple epidermal growth factor-like domains protein 6; Multiple EGF like domains 6. | RPL36A-HNRNPH2 readthrough; Belongs to the eukaryotic ribosomal protein eL42 family. | 0.479 |
| MEGF6 | WRAP73 | ENSP00000348982 | ENSP00000270708 | Multiple epidermal growth factor-like domains protein 6; Multiple EGF like domains 6. | WD repeat-containing protein WRAP73; The SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome. Required for the centrosomal localization of SSX2IP and normal mitotic bipolar spindle morphology. Required for the targeting of centriole satellite proteins to centrosomes such as of PCM1, SSX2IP, CEP290 and PIBF1/CEP90. Required for ciliogenesis and involved in the removal of the CEP97:CCP110 complex from the mother centriole. Involved in ciliary vesicle formation at the mother centriole and required for the docking of vesicles to the basal bo [...] | 0.889 |
| MEGF6 | ZBTB40 | ENSP00000348982 | ENSP00000384527 | Multiple epidermal growth factor-like domains protein 6; Multiple EGF like domains 6. | Zinc finger and BTB domain-containing protein 40; May be involved in transcriptional regulation. | 0.776 |
| MEGF6 | ZNF251 | ENSP00000348982 | ENSP00000292562 | Multiple epidermal growth factor-like domains protein 6; Multiple EGF like domains 6. | Zinc finger protein 251; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.462 |
| MFAP5 | MEGF6 | ENSP00000352455 | ENSP00000348982 | Microfibrillar-associated protein 5; May play a role in hematopoiesis. In the cardiovascular system, could regulate growth factors or participate in cell signaling in maintaining large vessel integrity (By similarity). Component of the elastin-associated microfibrils. | Multiple epidermal growth factor-like domains protein 6; Multiple EGF like domains 6. | 0.719 |
| MORN1 | MEGF6 | ENSP00000367792 | ENSP00000348982 | MORN repeat containing 1. | Multiple epidermal growth factor-like domains protein 6; Multiple EGF like domains 6. | 0.462 |
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