STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLAC9Placenta-specific protein 9; Placenta associated 9; Belongs to the PLAC9 family. (97 aa)    
Predicted Functional Partners:
EMILIN1
EMILIN-1; May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity.
   
   0.756
TMEM254
Transmembrane protein 254.
      
 0.608
DUXB
Double homeobox B.
      
 0.608
C14orf119
Uncharacterized protein C14orf119; Chromosome 14 open reading frame 119.
      
 0.525
ANXA11
Annexin A11; Binds specifically to calcyclin in a calcium-dependent manner (By similarity). Required for midbody formation and completion of the terminal phase of cytokinesis.
   
  
 0.473
ARGFX
Arginine-fifty homeobox; Putative transcription factor.
      
 0.460
DUXA
Double homeobox protein A; Putative transcription factor; Belongs to the paired homeobox family.
      
 0.448
DUX4
Double homeobox protein 4-like protein 2; May be involved in transcriptional regulation.
      
 0.440
PYROXD1
Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1; Probable FAD-dependent oxidoreductase; involved in the cellular oxidative stress response. Required for normal sarcomere structure and muscle fiber integrity (By similarity).
      
 0.434
EMC6
ER membrane protein complex subunit 6; Belongs to the EMC6 family.
    
   0.426
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.